ENSDARG00000030448


Danio rerio

Features
Gene ID: ENSDARG00000030448
  
Biological name :sppl2
  
Synonyms : signal peptide peptidase-like 2 / sppl2
  
Possible biological names infered from orthology : Q3TD49 / Q8TCT7 / signal peptide peptidase like 2B / SPPL2B
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 37480669
Gene end: 37503009
  
Corresponding Affymetrix probe sets: Dr.10224.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000032543
NCBI entrez gene - 325540     See in Manteia.
RefSeq - NM_001045244
RefSeq Peptide - NP_001038709
swissprot - F1QYI0
ZFIN ID - ZDB-GENE-030131-4265
Ensembl - ENSDARG00000030448
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SPPL2BENSGALG00000000430Gallus gallus
 Q8TCT7ENSG00000005206Homo sapiens
 Q3TD49ENSMUSG00000035206Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sppl3 / signal peptide peptidase 3 / Q8TCT6* / signal peptide peptidase like 3*ENSDARG0000002522017
hm13 / histocompatibility (minor) 13 / H13* / Q8TCT9* / Q9D8V0* / Minor histocompatibility antigen H13 *ENSDARG0000003784615


Protein motifs (from Interpro)
Interpro ID Name
 IPR003137  PA domain
 IPR006639  Presenilin/signal peptide peptidase
 IPR007369  Peptidase A22B, signal peptide peptidase
 IPR033149  Signal peptidase peptidase-like 2B


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0031293 membrane protein intracellular domain proteolysis IEA
 biological_processGO:0050819 negative regulation of coagulation IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004190 aspartic-type endopeptidase activity IEA
 molecular_functionGO:0042500 aspartic endopeptidase activity, intramembrane cleaving IEA


Pathways (from Reactome)
Pathway description
Regulation of TNFR1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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