ENSDARG00000037846


Danio rerio
membranehm13peptidaseintegralcomponentsignalpeptidesideendoplasmicreticulumpresenilinbproteolysisregulationneuronapoptoticprocesslysosomalgolgi-associatedvesiclecytoplasmiclumenalaspartic-typeendopeptidaseactivity

Features
Gene ID: ENSDARG00000037846
  
Biological name :hm13
  
Synonyms : histocompatibility (minor) 13 / hm13
  
Possible biological names infered from orthology : H13 / Minor histocompatibility antigen H13 / Q8TCT9 / Q9D8V0
  
Species: Danio rerio
  
Chr. number: 23
Strand: -1
Band:
Gene start: 480423
Gene end: 493384
  
Corresponding Affymetrix probe sets: Dr.20331.1.A1_at (Zebrafish Array)   NM_212572_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000109113
NCBI entrez gene - 259190     See in Manteia.
RefSeq - NM_212572
RefSeq Peptide - NP_997737
swissprot - Q6IQA7
ZFIN ID - ZDB-GENE-020802-3
Ensembl - ENSDARG00000037846
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HM13ENSGALG00000006207Gallus gallus
 HM13ENSG00000101294Homo sapiens
 H13ENSMUSG00000019188Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sppl3 / signal peptide peptidase 3 / Q8TCT6* / signal peptide peptidase like 3*ENSDARG0000002522025
sppl2 / signal peptide peptidase-like 2 / Q8TCT7* / Q3TD49* / SPPL2B* / signal peptide peptidase like 2B*ENSDARG0000003044823


Protein motifs (from Interpro)
Interpro ID Name
 IPR006639  Presenilin/signal peptide peptidase
 IPR007369  Peptidase A22B, signal peptide peptidase


Gene Ontology (GO)
nitrogen compound metabolic processprimary metabolic processorganic substance metabolic processcell deathnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processcell deathnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processcell deathnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processcell deathnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processcell deathnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processcell deathnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processcell deathnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processcell deathnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processcell deathnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processcell deathnitrogen compound metabolic processnitrogen compound metabolic processprimary metabolic processprimary metabolic processorganic substance metabolic processorganic substance metabolic processcell deathcell death
catalytic activity, acting on a proteinhydrolase activitycatalytic activity, acting on a proteinhydrolase activitycatalytic activity, acting on a proteinhydrolase activitycatalytic activity, acting on a proteinhydrolase activitycatalytic activity, acting on a proteinhydrolase activitycatalytic activity, acting on a proteinhydrolase activitycatalytic activity, acting on a proteinhydrolase activitycatalytic activity, acting on a proteinhydrolase activitycatalytic activity, acting on a proteinhydrolase activitycatalytic activity, acting on a proteinhydrolase activitycatalytic activity, acting on a proteincatalytic activity, acting on a proteinhydrolase activityhydrolase activity
cellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellcellmembranemembraneorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0043523 regulation of neuron apoptotic process IMP
 cellular_componentGO:0005765 lysosomal membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030660 Golgi-associated vesicle membrane IBA
 cellular_componentGO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane IBA
 cellular_componentGO:0071556 integral component of lumenal side of endoplasmic reticulum membrane IBA
 molecular_functionGO:0004190 aspartic-type endopeptidase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr