ENSG00000101294


Homo sapiens

Features
Gene ID: ENSG00000101294
  
Biological name :HM13
  
Synonyms : histocompatibility minor 13 / HM13 / Q8TCT9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q11.21
Gene start: 31514428
Gene end: 31577923
  
Corresponding Affymetrix probe sets: 1557148_at (Human Genome U133 Plus 2.0 Array)   1558561_at (Human Genome U133 Plus 2.0 Array)   224615_x_at (Human Genome U133 Plus 2.0 Array)   230107_at (Human Genome U133 Plus 2.0 Array)   232209_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000479020
Ensembl peptide - ENSP00000335294
Ensembl peptide - ENSP00000479443
Ensembl peptide - ENSP00000341347
Ensembl peptide - ENSP00000381237
Ensembl peptide - ENSP00000343032
NCBI entrez gene - 81502     See in Manteia.
OMIM - 607106
RefSeq - NM_178582
RefSeq - NM_030789
RefSeq - NM_178580
RefSeq - NM_178581
RefSeq Peptide - NP_110416
RefSeq Peptide - NP_848695
RefSeq Peptide - NP_848696
RefSeq Peptide - NP_848697
swissprot - Q8TCT9
swissprot - A0A0C4DGU3
swissprot - A0A087WVH6
swissprot - A0A075B6F6
swissprot - A0A0S2Z5V7
Ensembl - ENSG00000101294
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hm13ENSDARG00000037846Danio rerio
 HM13ENSGALG00000006207Gallus gallus
 H13ENSMUSG00000019188Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SPPL3 / Q8TCT6 / signal peptide peptidase like 3ENSG0000015783721
Q8TCT7 / SPPL2B / signal peptide peptidase like 2BENSG0000000520620
Q8TCT8 / SPPL2A / signal peptide peptidase like 2AENSG0000013860019
Q8IUH8 / SPPL2C / signal peptide peptidase like 2CENSG0000018529419


Protein motifs (from Interpro)
Interpro ID Name
 IPR006639  Presenilin/signal peptide peptidase
 IPR007369  Peptidase A22B, signal peptide peptidase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0033619 membrane protein proteolysis IDA
 biological_processGO:0051289 protein homotetramerization TAS
 biological_processGO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol IMP
 cellular_componentGO:0005765 lysosomal membrane IBA
 cellular_componentGO:0005783 endoplasmic reticulum ISS
 cellular_componentGO:0005789 endoplasmic reticulum membrane IC
 cellular_componentGO:0005791 rough endoplasmic reticulum IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030660 Golgi-associated vesicle membrane IBA
 cellular_componentGO:0036513 Derlin-1 retrotranslocation complex IDA
 cellular_componentGO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane IDA
 cellular_componentGO:0071556 integral component of lumenal side of endoplasmic reticulum membrane IDA
 molecular_functionGO:0004190 aspartic-type endopeptidase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0042500 aspartic endopeptidase activity, intramembrane cleaving IMP
 molecular_functionGO:0042803 protein homodimerization activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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