ENSDARG00000032103


Danio rerio

Features
Gene ID: ENSDARG00000032103
  
Biological name :mapk6
  
Synonyms : mapk6 / mitogen-activated protein kinase 6
  
Possible biological names infered from orthology : Q16659 / Q61532
  
Species: Danio rerio
  
Chr. number: 18
Strand: -1
Band:
Gene start: 39170127
Gene end: 39288894
  
Corresponding Affymetrix probe sets: Dr.24171.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000145345
Ensembl peptide - ENSDARP00000034206
Ensembl peptide - ENSDARP00000130447
Ensembl peptide - ENSDARP00000145971
NCBI entrez gene - 565830     See in Manteia.
swissprot - Q0H1F2
ZFIN ID - ZDB-GENE-050420-7
Ensembl - ENSDARG00000032103
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAPK6ENSGALG00000031448Gallus gallus
 MAPK6ENSG00000069956Homo sapiens
 Mapk6ENSMUSG00000042688Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mapk4 / mitogen-activated protein kinase 4 / P31152* / Q6P5G0*ENSDARG0000011058141
mapk7 / mitogen-activated protein kinase 7 / Q13164* / Q9WVS8*ENSDARG0000002311023
mapk1 / mitogen-activated protein kinase 1 / P28482* / P63085* / Mus musculus mitogen-activated protein kinase 1 (Mapk1), transcript variant 3, mRNA.*ENSDARG0000002755222
mapk3 / mitogen-activated protein kinase 3 / P27361* / Q63844*ENSDARG0000007057321
mapk15 / mitogen-activated protein kinase 15 / Q80Y86* / Q8TD08*ENSDARG0000010082219
nlk2 / nemo-like kinase, type 2 / NLK* / O54949* / Q9UBE8* / nemo like kinase* / Serine/threonine-protein kinase NLK *ENSDARG0000002879317
nlk1 / nemo-like kinase, type 1ENSDARG0000000656616


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR008350  Mitogen-activated protein (MAP) kinase, ERK3/4
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0010468 regulation of gene expression IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0071310 cellular response to organic substance IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004707 MAP kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA


Pathways (from Reactome)
Pathway description
MAPK6/MAPK4 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000027391 ccnd3 / cyclin D3 / P30281* / P30282* / G1/S-specific cyclin-D3 *  / complex / reaction
 ENSDARG00000052783 cdc42ep3 / CDC42 effector protein (Rho GTPase binding) 3 / Q9UKI2* / CDC42 effector protein 3*  / reaction
 ENSDARG00000062390 cdc42ep5 / CDC42 effector protein (Rho GTPase binding) 5 / Q6NZY7* / Q9Z0X0* / 1700027J19Rik* / CDC42 effector protein 5*  / reaction
 ENSDARG00000053959 cdc42ep2 / CDC42 effector protein (Rho GTPase binding) 2 / O14613* / Q8JZX9* / CDC42 effector protein 2*  / reaction
 ENSDARG00000077404 ncoa3 / nuclear receptor coactivator 3 / Q9Y6Q9*  / reaction
 ENSDARG00000057016 cdc14ab / A0A0R4IVA4 / cell division cycle 14Ab / CDC14A* / Q6GQT0* / Q9UNH5* / cell division cycle 14A* / Dual specificity protein phosphatase CDC14A *  / complex / reaction
 ENSDARG00000028082 mapkapk5 / mitogen-activated protein kinase-activated protein kinase 5 / Q8IW41*  / complex / reaction
 ENSDARG00000087554 cdk1 / cyclin-dependent kinase 1 / P06493* / P11440*  / reaction






 

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