ENSDARG00000033042


Danio rerio

Features
Gene ID: ENSDARG00000033042
  
Biological name :ptprja
  
Synonyms : protein tyrosine phosphatase, receptor type, J a / ptprja
  
Possible biological names infered from orthology : protein tyrosine phosphatase, receptor type J / PTPRJ / Q12913
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 39553046
Gene end: 39611109
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000124678
NCBI entrez gene - 559679     See in Manteia.
swissprot - B6HY54
ZFIN ID - ZDB-GENE-030131-8301
Ensembl - ENSDARG00000033042
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTPRJENSGALG00000006382Gallus gallus
 PTPRJENSG00000149177Homo sapiens
 PtprjENSMUSG00000025314Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ptprq / protein tyrosine phosphatase, receptor type, Q / P0C5E4* / Phosphatidylinositol phosphatase PTPRQ *ENSDARG0000000884919
ptprb / protein tyrosine phosphatase, receptor type, b / P23467*ENSDARG0000007662419
ptprh / protein tyrosine phosphatase, receptor type, hENSDARG0000007956014
ptprjb.1 / protein tyrosine phosphatase, receptor type, Jb, tandem duplicate 1 / PTPRJ* / Q12913* / protein tyrosine phosphatase, receptor type J*ENSDARG0000009153914
ptprh / protein tyrosine phosphatase, receptor type, hENSDARG0000007829713
ptprjb.2 / protein tyrosine phosphatase, receptor type, Jb, tandem duplicate 2 / PTPRJ* / Q12913* / protein tyrosine phosphatase, receptor type J*ENSDARG0000008651113
ptpro / protein tyrosine phosphatase, receptor type, O / E9Q612* / Q16827* / Receptor-type tyrosine-protein phosphatase O *ENSDARG000001104709
ptpn9b / protein tyrosine phosphatase, non-receptor type 9, bENSDARG000000739028
ptpn9a / protein tyrosine phosphatase, non-receptor type 9, a / PTPN9* / O35239* / P43378* / protein tyrosine phosphatase, non-receptor type 9*ENSDARG000000774958
ptpro / protein tyrosine phosphatase, receptor type, OENSDARG000001004227
ptpn18 / protein tyrosine phosphatase, non-receptor type 18 / Q61152* / Q99952*ENSDARG000000063086
ptpn2a / protein tyrosine phosphatase, non-receptor type 2, a / PTPN2* / P17706* / Q06180* / protein tyrosine phosphatase, non-receptor type 2* / Tyrosine-protein phosphatase non-receptor type 2 *ENSDARG000000164816
ptpn2b / protein tyrosine phosphatase, non-receptor type 2, b / PTPN2* / P17706* / Q06180* / protein tyrosine phosphatase, non-receptor type 2* / Tyrosine-protein phosphatase non-receptor type 2 *ENSDARG000000359866
ptpn22 / protein tyrosine phosphatase, non-receptor type 22 / P29352* / Q9Y2R2* / Tyrosine-protein phosphatase non-receptor type 22 *ENSDARG000001041976
ptpn1 / protein tyrosine phosphatase, non-receptor type 1 / P18031*ENSDARG000000079234


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0048844 artery morphogenesis IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Negative regulation of MET activity


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood decreased fluid flow , abnormal
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 ZFA:0000014 dorsal aorta dorsal aorta morphology , abnormal
dorsal aorta increased accumulation blood , abnormal
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 ZFA:0000477 posterior cardinal vein posterior cardinal vein increased accumulation blood , abnormal
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 ZFA:0001073 axial vasculature axial vasculature decreased functionality , abnormal
axial vasculature morphology , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000045544 hgfa / hepatocyte growth factor a / HGF* / P14210* / Q08048* / hepatocyte growth factor* / Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain*  / reaction
 ENSDARG00000070903 met / MET proto-oncogene, receptor tyrosine kinase / P08581*  / reaction






 

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