ENSDARG00000033539


Danio rerio

Features
Gene ID: ENSDARG00000033539
  
Biological name :paics
  
Synonyms : paics / phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
  
Possible biological names infered from orthology : Mus musculus phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase (Paics), transcript variant 5, mRNA. / P22234 / phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase / Q9DCL9
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 25618114
Gene end: 25631256
  
Corresponding Affymetrix probe sets: Dr.983.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000116949
Ensembl peptide - ENSDARP00000120562
Ensembl peptide - ENSDARP00000048163
Ensembl peptide - ENSDARP00000109219
NCBI entrez gene - 321193     See in Manteia.
swissprot - A0A0A0MPG9
swissprot - Q7ZUN6
ZFIN ID - ZDB-GENE-030131-9762
Ensembl - ENSDARG00000033539
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PAICSENSGALG00000013726Gallus gallus
 PAICSENSG00000128050Homo sapiens
 PaicsENSMUSG00000029247Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000031  PurE domain
 IPR018236  SAICAR synthetase, conserved site
 IPR028923  SAICAR synthetase/ADE2, N-terminal
 IPR033626  Class II PurE


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006164 purine nucleotide biosynthetic process IEA
 biological_processGO:0006189 "de novo" IMP biosynthetic process IEA
 biological_processGO:0043009 chordate embryonic development IMP
 biological_processGO:0043010 camera-type eye development IMP
 biological_processGO:0043473 pigmentation IMP
 biological_processGO:0060041 retina development in camera-type eye IMP
 molecular_functionGO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity IEA


Pathways (from Reactome)
Pathway description
Purine ribonucleoside monophosphate biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system degenerate , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
eye quality , abnormal
eye pigmented , abnormal
Show

 ZFA:0000144 retinal pigmented epithelium retinal pigmented epithelium quality , abnormal
retinal pigmented epithelium decreased pigmentation , abnormal
Show

 ZFA:0001094 whole organism whole organism dead , abnormal
whole organism decreased size , abnormal
Show

 ZFA:0001114 head head decreased width , abnormal
head decreased size , abnormal
Show

 ZFA:0009090 pigment cell pigment cell quality , abnormal
Show

 ZFA:0009091 melanocyte melanocyte pigment granule decreased amount , abnormal
Show

 ZFA:0009198 xanthophore xanthophore quality , abnormal
xanthophore absent , abnormal
xanthophore pigment granule decreased amount , abnormal
Show

 ZFA:0009199 iridophore iridophore pigment granule decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000033539 paics / phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase / P22234* / Q9DCL9* / phosphoribosylaminoimidazole carboxylase and phosphoribosy...  / complex






 

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