ENSDARG00000033647


Danio rerio

Features
Gene ID: ENSDARG00000033647
  
Biological name :smarcb1a
  
Synonyms : Q5U379 / smarcb1a / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1a
  
Possible biological names infered from orthology : Q12824 / Q9Z0H3 / SMARCB1 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 30929704
Gene end: 30944491
  
Corresponding Affymetrix probe sets: Dr.16141.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000109356
Ensembl peptide - ENSDARP00000049943
Ensembl peptide - ENSDARP00000150055
NCBI entrez gene - 799716     See in Manteia.
RefSeq - NM_001007296
RefSeq - XM_005167183
RefSeq Peptide - NP_001007297
swissprot - F6NQ54
swissprot - A8WG87
swissprot - Q5U379
ZFIN ID - ZDB-GENE-041114-5
Ensembl - ENSDARG00000033647
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q5ZK40ENSGALG00000005983Gallus gallus
 Q12824ENSG00000099956Homo sapiens
 Q9Z0H3ENSMUSG00000000902Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
smarcb1b / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b / Q12824* / Q9Z0H3* / SMARCB1* / SWI/SNF related, matrix associated, actin depe...ENSDARG0000001159495


Protein motifs (from Interpro)
Interpro ID Name
 IPR006939  SNF5/SMARCB1/INI1
 IPR017393  Chromatin-remodeling complex component Sfh1/SNF5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IBA
 biological_processGO:0006337 nucleosome disassembly IBA
 biological_processGO:0006338 chromatin remodeling IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0008285 negative regulation of cell proliferation IBA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0043044 ATP-dependent chromatin remodeling IBA
 cellular_componentGO:0000228 nuclear chromosome IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding ISS


Pathways (from Reactome)
Pathway description
RMTs methylate histone arginines
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000008904 smarca2 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 / P51531*  / complex
 ENSDARG00000077946 smarcc2 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 / Q6PDG5* / Q8TAQ2* / SWI/SNF complex subunit SMARCC2 *  / complex
 ENSDARG00000017397 smarcc1a / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1a / P97496* / Q92922* / SMARCC1* / SWI/SNF related, matrix associated, actin depe...  / complex
 ENSDARG00000077226 smarca4a / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a / P51532* / Q3TKT4* / SMARCA4* / SWI/SNF related, matrix associated, actin depe...  / complex
 ENSDARG00000087646 runx1 / runt-related transcription factor 1 / Q01196*  / complex / reaction






 

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