ENSDARG00000037283


Danio rerio

Features
Gene ID: ENSDARG00000037283
  
Biological name :plrg1
  
Synonyms : pleiotropic regulator 1 / plrg1
  
Possible biological names infered from orthology : O43660 / Q922V4
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 25650917
Gene end: 25666604
  
Corresponding Affymetrix probe sets: Dr.11443.1.S1_at (Zebrafish Array)   NM_213440_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000054234
NCBI entrez gene - 100004402     See in Manteia.
RefSeq - NM_213440
RefSeq Peptide - NP_998605
swissprot - Q5U3B5
ZFIN ID - ZDB-GENE-040426-2787
Ensembl - ENSDARG00000037283
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLRG1ENSGALG00000009257Gallus gallus
 PLRG1ENSG00000171566Homo sapiens
 Plrg1ENSMUSG00000027998Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
strn4 / striatin, calmodulin binding protein 4 / Q9NRL3* / striatin 4*ENSDARG0000010290219
strn3 / striatin, calmodulin binding protein 3 / Q13033* / Q9ERG2* / striatin 3*ENSDARG0000000172918
strn / striatin, calmodulin binding protein / O43815* / striatin*ENSDARG0000010001118


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IBA
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator IMP
 cellular_componentGO:0000974 Prp19 complex IBA
 cellular_componentGO:0005662 DNA replication factor A complex IBA
 cellular_componentGO:0071011 precatalytic spliceosome IBA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IBA
 cellular_componentGO:0080008 Cul4-RING E3 ubiquitin ligase complex IBA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000084 yolk yolk quality , abnormal
yolk circular , abnormal
yolk grey , abnormal
Show

 ZFA:0000106 extension extension decreased thickness , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0001094 whole organism whole organism shape , abnormal
whole organism apoptotic , abnormal
whole organism necrotic , abnormal
whole organism viability , abnormal
Show

 ZFA:0001114 head head flat , abnormal
Show

 ZFA:0001115 trunk trunk decreased length , abnormal
trunk decreased thickness , abnormal
Show

 ZFA:0001117 post-vent region post-vent region truncated , abnormal
Show

 ZFA:0009248 neuron neuron increased sensitivity to irradiation , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr