ENSDARG00000037488


Danio rerio

Features
Gene ID: ENSDARG00000037488
  
Biological name :canx
  
Synonyms : calnexin / canx
  
Possible biological names infered from orthology : P27824 / P35564
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 16432738
Gene end: 16476863
  
Corresponding Affymetrix probe sets: Dr.6391.1.S1_at (Zebrafish Array)   NM_213448_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000083454
NCBI entrez gene - 406757     See in Manteia.
RefSeq - NM_213448
RefSeq - XM_009307813
RefSeq Peptide - NP_998613
swissprot - F1QKS4
ZFIN ID - ZDB-GENE-040426-2797
Ensembl - ENSDARG00000037488
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CANXENSGALG00000032148Gallus gallus
 CANXENSG00000127022Homo sapiens
 CanxENSMUSG00000020368Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
clgn / calmegin / O14967* / P52194* / Mus musculus calmegin (Clgn), transcript variant 2, mRNA.*ENSDARG0000000931559
si:ch211-274f20.2ENSDARG0000005857931
calr3b / calreticulin 3bENSDARG0000010280828
calr / calreticulin / P14211* / P27797*ENSDARG0000007629027
calr3a / calreticulin 3aENSDARG0000010397927


Protein motifs (from Interpro)
Interpro ID Name
 IPR001580  Calreticulin/calnexin
 IPR009033  Calreticulin/calnexin, P domain superfamily
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR018124  Calreticulin/calnexin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0048916 posterior lateral line development IMP
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
MHC class II antigen presentation
Calnexin/calreticulin cycle
Interleukin-27 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000243 neuromast neuromast decreased amount , abnormal
Show

 ZFA:0001157 posterior lateral line primordium posterior lateral line primordium neuromast decreased amount , abnormal
posterior lateral line primordium apoptotic process increased occurrence , abnormal
posterior lateral line primordium cell proliferation decreased occurrence , abnormal
Show

 ZFA:0009367 neuromast hair cell neuromast hair cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000009087 cd74a / CD74 molecule, major histocompatibility complex, class II invariant chain a / CD74* / P04233* / P04441* / CD74 molecule* / CD74 antigen (invariant polypeptide of major histocompatib...  / complex / reaction
 ENSDARG00000102640 pdia3 / protein disulfide isomerase family A, member 3 / P27773* / P30101* / Protein disulfide-isomerase A3 *  / complex / reaction
 ENSDARG00000076290 calr / calreticulin / P14211* / P27797*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr