ENSDARG00000076290


Danio rerio

Features
Gene ID: ENSDARG00000076290
  
Biological name :calr
  
Synonyms : calr / calreticulin
  
Possible biological names infered from orthology : P14211 / P27797
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 16582339
Gene end: 16592491
  
Corresponding Affymetrix probe sets: Dr.11394.1.S1_at (Zebrafish Array)   Dr.1809.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000092429
NCBI entrez gene - 325317     See in Manteia.
swissprot - F1Q8W8
ZFIN ID - ZDB-GENE-030131-4042
Ensembl - ENSDARG00000076290
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CALRENSGALG00000040368Gallus gallus
 CALRENSG00000179218Homo sapiens
 CalrENSMUSG00000003814Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
calr3b / calreticulin 3bENSDARG0000010280871
calr3a / calreticulin 3aENSDARG0000010397971
clgn / calmegin / O14967* / P52194* / Mus musculus calmegin (Clgn), transcript variant 2, mRNA.*ENSDARG0000000931543
canx / calnexin / P27824* / P35564*ENSDARG0000003748839
si:ch211-274f20.2ENSDARG0000005857922


Protein motifs (from Interpro)
Interpro ID Name
 IPR001580  Calreticulin/calnexin
 IPR009033  Calreticulin/calnexin, P domain superfamily
 IPR009169  Calreticulin
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR018124  Calreticulin/calnexin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
ER-Phagosome pathway
Calnexin/calreticulin cycle
Antigen Presentation: Folding, assembly and peptide loading of class I MHC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000033446 tap2t / transporter associated with antigen processing, subunit type t, teleost specific / TAP2* / Q03519* / P36371* / AL669918.1* / transporter 2, ATP binding cassette subfamily B member* ...  / reaction
 ENSDARG00000037488 canx / calnexin / P27824* / P35564*  / complex
 ENSDARG00000102640 pdia3 / protein disulfide isomerase family A, member 3 / P27773* / P30101* / Protein disulfide-isomerase A3 *  / complex / reaction
 ENSDARG00000079402 tapbp.1 / TAP binding protein (tapasin), tandem duplicate 1 / TAPBP* / O15533* / TAP binding protein*  / reaction
 ENSDARG00000079766 tap1 / transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) / P21958* / Q03518* / transporter 1, ATP binding cassette subfamily B member*  / reaction
 ENSDARG00000100435 Q7SXP0 / sec22bb / SEC22 homolog B, vesicle trafficking protein b / SEC22B* / O08547* / O75396* / Vesicle-trafficking protein SEC22b * / SEC22 homolog B, vesicle trafficking protein (gene/p...  / reaction
 ENSDARG00000045011 tapbp.2 / TAP binding protein (tapasin), tandem duplicate 2 / TAPBP* / O15533* / TAP binding protein*  / reaction






 

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