ENSDARG00000079766


Danio rerio

Features
Gene ID: ENSDARG00000079766
  
Biological name :tap1
  
Synonyms : tap1 / transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
  
Possible biological names infered from orthology : P21958 / Q03518 / transporter 1, ATP binding cassette subfamily B member
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 48678655
Gene end: 48708045
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000124923
Ensembl peptide - ENSDARP00000148638
NCBI entrez gene - 100333043     See in Manteia.
RefSeq - XM_002665007
swissprot - E7F8A9
ZFIN ID - ZDB-GENE-050517-43
Ensembl - ENSDARG00000079766
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TAP1ENSGALG00000035075Gallus gallus
 TAP1ENSG00000168394Homo sapiens
 Tap1ENSMUSG00000037321Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
abcb9 / ATP-binding cassette, sub-family B (MDR/TAP), member 9 / Q9JJ59* / Q9NP78* / ATP binding cassette subfamily B member 9*ENSDARG0000005620039
tap2a / transporter associated with antigen processing, subunit type a / TAP2* / Q03519* / P36371* / AL669918.1* / transporter 2, ATP binding cassette subfamily B member* / transporter 2, A...ENSDARG0000003678737
tap2t / transporter associated with antigen processing, subunit type t, teleost specific / TAP2* / Q03519* / P36371* / AL669918.1* / transporter 2, ATP binding cassette subfamily B member* ...ENSDARG0000003344633
abcb10 / ATP-binding cassette, sub-family B (MDR/TAP), member 10 / Q9JI39* / Q9NRK6* / ATP binding cassette subfamily B member 10*ENSDARG0000006159130
abcb8 / ATP-binding cassette, sub-family B (MDR/TAP), member 8 / Q9CXJ4* / Q9NUT2* / ATP binding cassette subfamily B member 8*ENSDARG0000005667228


Protein motifs (from Interpro)
Interpro ID Name
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR011527  ABC transporter type 1, transmembrane domain
 IPR013306  Antigen peptide transporter 1
 IPR017871  ABC transporter, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015833 peptide transport IEA
 biological_processGO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I IEA
 biological_processGO:0042886 amide transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IEA
 cellular_componentGO:0042825 TAP complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0015440 peptide-transporting ATPase activity IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0042287 MHC protein binding IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IEA
 molecular_functionGO:0046979 TAP2 binding IEA


Pathways (from Reactome)
Pathway description
ER-Phagosome pathway
Antigen Presentation: Folding, assembly and peptide loading of class I MHC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000033446 tap2t / transporter associated with antigen processing, subunit type t, teleost specific / TAP2* / Q03519* / P36371* / AL669918.1* / transporter 2, ATP binding cassette subfamily B member* ...  / complex
 ENSDARG00000076290 calr / calreticulin / P14211* / P27797*  / reaction
 ENSDARG00000079402 tapbp.1 / TAP binding protein (tapasin), tandem duplicate 1 / TAPBP* / O15533* / TAP binding protein*  / reaction
 ENSDARG00000100435 Q7SXP0 / sec22bb / SEC22 homolog B, vesicle trafficking protein b / SEC22B* / O08547* / O75396* / Vesicle-trafficking protein SEC22b * / SEC22 homolog B, vesicle trafficking protein (gene/p...  / reaction
 ENSDARG00000045011 tapbp.2 / TAP binding protein (tapasin), tandem duplicate 2 / TAPBP* / O15533* / TAP binding protein*  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr