ENSDARG00000100435


Danio rerio

Features
Gene ID: ENSDARG00000100435
  
Biological name :sec22bb
  
Synonyms : Q7SXP0 / sec22bb / SEC22 homolog B, vesicle trafficking protein b
  
Possible biological names infered from orthology : O08547 / O75396 / SEC22B / SEC22 homolog B, vesicle trafficking protein (gene/pseudogene) / Vesicle-trafficking protein SEC22b
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 19504011
Gene end: 19512270
  
Corresponding Affymetrix probe sets: Dr.3020.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000136767
Ensembl peptide - ENSDARP00000137821
NCBI entrez gene - 327277     See in Manteia.
RefSeq - NM_001328526
RefSeq - NM_201302
RefSeq Peptide - NP_001315455
RefSeq Peptide - NP_958459
swissprot - A0A0R4IQP5
swissprot - Q7SXP0
swissprot - A7MCK9
ZFIN ID - ZDB-GENE-030131-5488
Ensembl - ENSDARG00000100435
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q5ZJW4ENSGALG00000039704Gallus gallus
 O75396ENSG00000265808Homo sapiens
 O08547ENSMUSG00000027879Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sec22ba / SEC22 homolog B, vesicle trafficking protein a / O75396* / SEC22B* / O08547* / Vesicle-trafficking protein SEC22b * / SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)*ENSDARG0000003010887
sec22a / SEC22 homolog A, vesicle trafficking protein / Q8BH47* / Q96IW7*ENSDARG0000007832830
sec22c / SEC22 homolog C, vesicle trafficking protein / Q8BXT9* / Q9BRL7* / Vesicle-trafficking protein SEC22c *ENSDARG0000006338727


Protein motifs (from Interpro)
Interpro ID Name
 IPR001388  Synaptobrevin
 IPR010908  Longin domain
 IPR011012  Longin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0048280 vesicle fusion with Golgi apparatus IBA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031201 SNARE complex IBA
 cellular_componentGO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane IEA
 cellular_componentGO:0042470 melanosome IEA
 molecular_functionGO:0000149 SNARE binding IBA
 molecular_functionGO:0005484 SNAP receptor activity IBA


Pathways (from Reactome)
Pathway description
ER-Phagosome pathway
COPII-mediated vesicle transport
Cargo concentration in the ER
COPI-dependent Golgi-to-ER retrograde traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000034885 bet1 / Bet1 golgi vesicular membrane trafficking protein / O15155* / O35623* / BET1 homolog *  / complex / reaction
 ENSDARG00000019581 uso1 / USO1 vesicle transport factor / O60763* / Q9Z1Z0* / USO1 vesicle docking factor*  / complex / reaction
 ENSDARG00000020405 napab / N-ethylmaleimide-sensitive factor attachment protein, alpha b / NAPA* / Q9DB05* / P54920* / NSF attachment protein alpha* / Alpha-soluble NSF attachment protein *  / complex / reaction
 ENSDARG00000006125 Q6P3K7 / csnk1db / casein kinase 1, delta b / Q9DC28* / CSNK1D* / P48730* / casein kinase 1 delta*  / reaction
 ENSDARG00000025033 stx5a / syntaxin 5A / STX5* / Q8K1E0* / Q13190* / syntaxin 5*  / complex / reaction
 ENSDARG00000033446 tap2t / transporter associated with antigen processing, subunit type t, teleost specific / TAP2* / Q03519* / P36371* / AL669918.1* / transporter 2, ATP binding cassette subfamily B member* ...  / reaction
 ENSDARG00000035763 stx18 / Q4VBI7 / syntaxin 18 / Q9P2W9*  / complex
 ENSDARG00000008370 Q7T2E3 / csnk1da / casein kinase 1, delta a / CSNK1D* / P48730* / casein kinase 1 delta*  / reaction
 ENSDARG00000029663 rab1ab / RAB1A, member RAS oncogene family b / Rab1* / RAB1A* / P62821* / P62820* / Ras-related protein Rab-1A * / RAB1A, member RAS oncogene family*  / complex / reaction
 ENSDARG00000038991 nsfb / N-ethylmaleimide-sensitive factor b / NSF* / P46459* / P46460* / Vesicle-fusing ATPase * / N-ethylmaleimide sensitive factor, vesicle fusing ATPase*  / reaction / complex
 ENSDARG00000054807 sec13 / SEC13 homolog, nuclear pore and COPII coat complex component / P55735* / Q9D1M0*  / complex / reaction
 ENSDARG00000053070 gosr2 / golgi SNAP receptor complex member 2 / O14653* / O35166* / AC005670.2*  / complex / reaction
 ENSDARG00000063197 golga2 / golgin A2 / A6NMD2* / A7E2F4* / A8MQT2* / A8MZA4* / D6RF30* / F8WBI6* / A6NCC3* / A6NDK9* / A6NDN3* / H3BSY2* / I6L899* / P0CG33* / P0CJ92* / Q08379* / Q08AF8* / Q8N9W4* / Q921M4* ...  / complex / reaction
 ENSDARG00000007654 nsfa / N-ethylmaleimide-sensitive factor a / NSF* / P46459* / P46460* / Vesicle-fusing ATPase * / N-ethylmaleimide sensitive factor, vesicle fusing ATPase*  / reaction / complex
 ENSDARG00000021082 sec31a / SEC31 homolog A, COPII coat complex component / O94979* / Q3UPL0* / Protein transport protein Sec31A *  / complex / reaction
 ENSDARG00000079402 tapbp.1 / TAP binding protein (tapasin), tandem duplicate 1 / TAPBP* / O15533* / TAP binding protein*  / reaction
 ENSDARG00000078259 bnip1a / BCL2 interacting protein 1a / BNIP1* / Q6QD59* / Q12981* / BCL2 interacting protein 1* / Vesicle transport protein SEC20 *  / complex
 ENSDARG00000071906 sec24b / SEC24 homolog B, COPII coat complex component / O95487* / Sec24 related gene family, member B (S. cerevisiae)*  / complex / reaction
 ENSDARG00000079766 tap1 / transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) / P21958* / Q03518* / transporter 1, ATP binding cassette subfamily B member*  / reaction
 ENSDARG00000103516 sec24c / SEC24 homolog C, COPII coat complex component / P53992* / Sec24 related gene family, member C (S. cerevisiae)*  / complex / reaction
 ENSDARG00000003641 tfg / trk-fused gene / Q92734*  / complex / reaction
 ENSDARG00000052518 stx4 / syntaxin 4 / Stx4a* / P70452* / Q12846*  / complex
 ENSDARG00000076290 calr / calreticulin / P14211* / P27797*  / reaction
 ENSDARG00000104230 Q7SZE5 / sec23a / Sec23 homolog A, COPII coat complex component / Q15436* / Q01405* / Protein transport protein Sec23A * / Sec23 homolog A, coat complex II component*  / complex / reaction
 ENSDARG00000099554 sec16b / SEC16 homolog B, endoplasmic reticulum export factor / Q91XT4* / Q96JE7* / Protein transport protein Sec16B *  / complex / reaction
 ENSDARG00000104375 sec24a / SEC24 homolog A, COPII coat complex component / O95486*  / complex / reaction
 ENSDARG00000103403 sar1b / secretion associated, Ras related GTPase 1B / Q9Y6B6*  / complex / reaction
 ENSDARG00000104280 bnip1b / BCL2 interacting protein 1b / BNIP1* / Q12981* / BCL2 interacting protein 1*  / complex
 ENSDARG00000045011 tapbp.2 / TAP binding protein (tapasin), tandem duplicate 2 / TAPBP* / O15533* / TAP binding protein*  / reaction






 

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