ENSDARG00000103403


Danio rerio

Features
Gene ID: ENSDARG00000103403
  
Biological name :sar1b
  
Synonyms : sar1b / secretion associated, Ras related GTPase 1B
  
Possible biological names infered from orthology : Q9CQC9 / Q9Y6B6
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 45673433
Gene end: 45685063
  
Corresponding Affymetrix probe sets: Dr.10893.1.A1_at (Zebrafish Array)   NM_001024377_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000136017
NCBI entrez gene - 554177     See in Manteia.
RefSeq - NM_001024377
RefSeq Peptide - NP_001019548
swissprot - Q6PBX2
ZFIN ID - ZDB-GENE-040426-1958
Ensembl - ENSDARG00000103403
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SAR1BENSGALG00000038753Gallus gallus
 SAR1BENSG00000152700Homo sapiens
 Sar1bENSMUSG00000020386Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sar1ab / secretion associated, Ras related GTPase 1Ab / SAR1A* / Q9NR31* / secretion associated Ras related GTPase 1A*ENSDARG0000003332087


Protein motifs (from Interpro)
Interpro ID Name
 IPR005225  Small GTP-binding protein domain
 IPR006687  Small GTPase superfamily, SAR1-type
 IPR006689  Small GTPase superfamily, ARF/SAR type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0007417 central nervous system development IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0030299 intestinal cholesterol absorption IMP
 biological_processGO:0035265 organ growth IMP
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport
MHC class II antigen presentation
Cargo concentration in the ER
Chylomicron assembly
Antigen Presentation: Folding, assembly and peptide loading of class I MHC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000123 liver liver decreased size , abnormal
liver organ growth decreased process quality , abnormal
Show

 ZFA:0000140 pancreas pancreas decreased size , abnormal
pancreas organ growth decreased process quality , abnormal
Show

 ZFA:0000445 optic tectum optic tectum white matter position , abnormal
optic tectum white matter decreased size , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
Show

 ZFA:0001114 head head anterior-posterior axis decreased length , abnormal
Show

 ZFA:0001161 pectoral fin pectoral fin kinked , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage decreased size , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton malformed , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage malformed , abnormal
Show

 ZFA:0001440 rhombic lip rhombic lip white matter position , abnormal
rhombic lip white matter decreased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000009087 cd74a / CD74 molecule, major histocompatibility complex, class II invariant chain a / CD74* / P04233* / P04441* / CD74 molecule* / CD74 antigen (invariant polypeptide of major histocompatib...  / complex / reaction
 ENSDARG00000054807 sec13 / SEC13 homolog, nuclear pore and COPII coat complex component / P55735* / Q9D1M0*  / complex / reaction
 ENSDARG00000021082 sec31a / SEC31 homolog A, COPII coat complex component / O94979* / Q3UPL0* / Protein transport protein Sec31A *  / complex / reaction
 ENSDARG00000071906 sec24b / SEC24 homolog B, COPII coat complex component / O95487* / Sec24 related gene family, member B (S. cerevisiae)*  / complex / reaction
 ENSDARG00000103516 sec24c / SEC24 homolog C, COPII coat complex component / P53992* / Sec24 related gene family, member C (S. cerevisiae)*  / complex / reaction
 ENSDARG00000100435 Q7SXP0 / sec22bb / SEC22 homolog B, vesicle trafficking protein b / SEC22B* / O08547* / O75396* / Vesicle-trafficking protein SEC22b * / SEC22 homolog B, vesicle trafficking protein (gene/p...  / complex / reaction
 ENSDARG00000104230 Q7SZE5 / sec23a / Sec23 homolog A, COPII coat complex component / Q15436* / Q01405* / Protein transport protein Sec23A * / Sec23 homolog A, coat complex II component*  / complex / reaction
 ENSDARG00000099554 sec16b / SEC16 homolog B, endoplasmic reticulum export factor / Q91XT4* / Q96JE7* / Protein transport protein Sec16B *  / complex
 ENSDARG00000104375 sec24a / SEC24 homolog A, COPII coat complex component / O95486*  / complex / reaction
 ENSDARG00000003641 tfg / trk-fused gene / Q92734*  / complex
 ENSDARG00000053136 b2m / Q04475 / beta-2-microglobulin / P01887* / P61769*  / complex
 ENSDARG00000071168 zmp:0000001138 / B2M* / P61769* / beta-2-microglobulin*  / complex
 ENSDARG00000015887 b2ml / beta-2-microglobulin, like / B2M* / P01887* / P61769* / beta-2-microglobulin*  / complex
 ENSDARG00000101602 preb / prolactin regulatory element binding / Q9HCU5* / Q9WUQ2*  / reaction






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr