ENSG00000265808


Homo sapiens

Features
Gene ID: ENSG00000265808
  
Biological name :SEC22B
  
Synonyms : O75396 / SEC22B / SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p12
Gene start: 120150898
Gene end: 120176515
  
Corresponding Affymetrix probe sets: 209206_at (Human Genome U133 Plus 2.0 Array)   209207_s_at (Human Genome U133 Plus 2.0 Array)   214257_s_at (Human Genome U133 Plus 2.0 Array)   231890_at (Human Genome U133 Plus 2.0 Array)   233020_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000484017
Ensembl peptide - ENSP00000463393
NCBI entrez gene - 9554     See in Manteia.
OMIM - 604029
RefSeq - XM_017002857
RefSeq - NM_004892
RefSeq - XM_017002856
RefSeq Peptide - NP_004883
swissprot - O75396
swissprot - A0A087X1A9
Ensembl - ENSG00000265808
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q7SXP0ENSDARG00000100435Danio rerio
 sec22baENSDARG00000030108Danio rerio
 Q5ZJW4ENSGALG00000039704Gallus gallus
 O08547ENSMUSG00000027879Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96IW7 / SEC22A / SEC22 homolog A, vesicle trafficking proteinENSG0000012154232
Q9BRL7 / SEC22C / SEC22 homolog C, vesicle trafficking proteinENSG0000009318323


Protein motifs (from Interpro)
Interpro ID Name
 IPR001388  Synaptobrevin
 IPR010908  Longin domain
 IPR011012  Longin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent TAS
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport TAS
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER TAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0045732 positive regulation of protein catabolic process IMP
 biological_processGO:0048208 COPII vesicle coating TAS
 biological_processGO:0048280 vesicle fusion with Golgi apparatus IBA
 biological_processGO:1902902 negative regulation of autophagosome assembly IMP
 biological_processGO:1990668 vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane TAS
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0012507 ER to Golgi transport vesicle membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030133 transport vesicle TAS
 cellular_componentGO:0030670 phagocytic vesicle membrane TAS
 cellular_componentGO:0031201 SNARE complex IBA
 cellular_componentGO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane IEA
 cellular_componentGO:0042470 melanosome IEA
 molecular_functionGO:0000149 SNARE binding IBA
 molecular_functionGO:0005484 SNAP receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019905 syntaxin binding IEA


Pathways (from Reactome)
Pathway description
ER-Phagosome pathway
COPII-mediated vesicle transport
Cargo concentration in the ER
COPI-dependent Golgi-to-ER retrograde traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000108433 GOSR2 / O14653 / golgi SNAP receptor complex member 2  / complex / reaction
 ENSG00000105829 BET1 / O15155 / Bet1 golgi vesicular membrane trafficking protein  / complex / reaction
 ENSG00000138674 O94979 / SEC31A / SEC31 homolog A, COPII coat complex component  / complex / reaction
 ENSG00000105402 NAPA / P54920 / NSF attachment protein alpha  / complex / reaction
 ENSG00000138768 USO1 / O60763 / USO1 vesicle transport factor  / complex / reaction
 ENSG00000162236 STX5 / Q13190 / syntaxin 5  / complex / reaction
 ENSG00000141551 CSNK1D / P48730 / casein kinase 1 delta  / reaction
 ENSG00000100934 Q15436 / SEC23A / Sec23 homolog A, coat complex II component  / complex / reaction
 ENSG00000103496 STX4 / Q12846 / syntaxin 4  / complex
 ENSG00000092108 SCFD1 / Q8WVM8 / sec1 family domain containing 1  / complex / reaction
 ENSG00000157020 SEC13 / P55735 / SEC13 homolog, nuclear pore and COPII coat complex component  / complex / reaction
 ENSG00000107651 Q9Y6Y8 / SEC23IP / SEC23 interacting protein  / complex / reaction
 ENSG00000138069 RAB1A / P62820 / RAB1A, member RAS oncogene family  / complex / reaction
 ENSG00000073969 NSF / P46459 / N-ethylmaleimide sensitive factor, vesicle fusing ATPase  / complex / reaction
 ENSG00000114354 TFG / Q92734 / TRK-fused gene  / complex / reaction
 ENSG00000113734 BNIP1 / Q12981 / BCL2 interacting protein 1  / complex
 ENSG00000138802 O95487 / SEC24B / SEC24 homolog B, COPII coat complex component  / complex / reaction
 ENSG00000053501 USE1 / Q9NZ43 / unconventional SNARE in the ER 1  / complex
 ENSG00000148396 O15027 / SEC16A / SEC16 homolog A, endoplasmic reticulum export factor  / complex / reaction
 ENSG00000120341 Q96JE7 / SEC16B / SEC16 homolog B, endoplasmic reticulum export factor  / complex / reaction
 ENSG00000168818 STX18 / Q9P2W9 / syntaxin 18  / complex
 ENSG00000150961 O94855 / SEC24D / SEC24 homolog D, COPII coat complex component  / complex / reaction
 ENSG00000179218 CALR / P27797 / calreticulin  / reaction
 ENSG00000176986 P53992 / SEC24C / SEC24 homolog C, COPII coat complex component  / complex / reaction
 ENSG00000113615 O95486 / SEC24A / SEC24 homolog A, COPII coat complex component  / complex / reaction
 ENSG00000114745 Q9BQQ3 / GORASP1 / golgi reassembly stacking protein 1  / complex / reaction
 ENSG00000168394 TAP1 / Q03518 / transporter 1, ATP binding cassette subfamily B member  / reaction
 ENSG00000204267 TAP2 / Q03519 / transporter 2, ATP binding cassette subfamily B member  / reaction
 ENSG00000152700 SAR1B / Q9Y6B6 / secretion associated Ras related GTPase 1B  / complex / reaction
 ENSG00000167110 GOLGA2 / Q08379 / golgin A2  / complex / reaction
 ENSG00000231925 TAPBP / O15533 / TAP binding protein  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr