ENSDARG00000037550


Danio rerio

Features
Gene ID: ENSDARG00000037550
  
Biological name :cyp21a2
  
Synonyms : cyp21a2 / cytochrome P450, family 21, subfamily A, polypeptide 2
  
Possible biological names infered from orthology : Cyp21a1 / cytochrome P450 family 21 subfamily A member 2 / P08686
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 16605517
Gene end: 16619897
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000149944
Ensembl peptide - ENSDARP00000125284
Ensembl peptide - ENSDARP00000146613
Ensembl peptide - ENSDARP00000151613
NCBI entrez gene - 793249     See in Manteia.
swissprot - H0WEK6
ZFIN ID - ZDB-GENE-070103-6
Ensembl - ENSDARG00000037550
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYP21A1ENSGALG00000039742Gallus gallus
 P08686ENSG00000231852Homo sapiens
 Cyp21a1ENSMUSG00000024365Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cyp17a1 / cytochrome P450, family 17, subfamily A, polypeptide 1 / P05093* / P27786* / Steroid 17-alpha-hydroxylase/17,20 lyase * / cytochrome P450 family 17 subfamily A member 1*ENSDARG0000003356630
cyp17a2 / cytochrome P450, family 17, subfamily A, polypeptide 2ENSDARG0000005396630
cyp2x9 / cytochrome P450, family 2, subfamily X, polypeptide 9ENSDARG0000007077526
cyp2x6 / cytochrome P450, family 2, subfamily X, polypeptide 6 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000007965326
cyp2x7 / cytochrome P450, family 2, subfamily X, polypeptide 7 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000004400225
cyp2x8 / cytochrome P450, family 2, subfamily X, polypeptide 8 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000004399724
cyp1a / cytochrome P450, family 1, subfamily A / P05177* / CYP1A1* / CYP1A2* / P00184* / P00186* / P04798* / Cytochrome P450 1A1 * / Cytochrome P450 1A2 * / cytochrome P450 family 1 subfami...ENSDARG0000009831524
cyp2x10.2 / cytochrome P450, family 2, subfamily X, polypeptide 10.2 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000000650123
cyp1d1 / cytochrome P450, family 1, subfamily D, polypeptide 1ENSDARG0000003556923
cyp2x10.2 / cytochrome P450, family 2, subfamily X, polypeptide 10.2 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000006828323
cyp2x12 / cytochrome P450, family 2, subfamily X, polypeptide 12 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000006829022
cyp1b1 / cytochrome P450, family 1, subfamily B, polypeptide 1 / Q16678* / Q64429* / Cytochrome P450 1B1 * / cytochrome P450 family 1 subfamily B member 1*ENSDARG0000006893422
cyp2x12 / cytochrome P450, family 2, subfamily X, polypeptide 12 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000009209122
cyp2aa4 / cytochrome P450, family 2, subfamily AA, polypeptide 4 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000009880322
cyp1c2 / cytochrome P450, family 1, subfamily C, polypeptide 2ENSDARG0000010178922
cyp2aa9 / cytochrome P450, family 2, subfamily AA, polypeptide 9 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000009889021
cyp2aa1 / cytochrome P450, family 2, subfamily AA, polypeptide 1 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000009900321
cyp2aa8 / cyp2aa9 / cytochrome P450, family 2, subfamily AA, polypeptide 8 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000010454021
cyp2aa2 / y cytochrome P450, family 2, subfamily AA, polypeptide 2 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000010481121
cyp2aa11 / cyp2aa12 / cytochrome P450, family 2, subfamily AA, polypeptide 11 / Cyp2ab1* / cytochrome P450, family 2, subfamily ab, polypeptide 1*ENSDARG0000010280520


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR017972  Cytochrome P450, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Mineralocorticoid biosynthesis
Glucocorticoid biosynthesis
Endogenous sterols


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000118 hypophysis hypophysis increased size , abnormal
Show

 ZFA:0001094 whole organism whole organism increased amount , abnormal
whole organism decreased amount , abnormal
whole organism 17alpha-hydroxyprogesterone present , abnormal
whole organism cortisol decreased amount , abnormal
whole organism 21-deoxycortisol present , abnormal
whole organism 21-deoxycortisol increased amount , abnormal
Show

 ZFA:0001271 neurohypophysis neurohypophysis increased distribution , abnormal
Show

 ZFA:0001282 adenohypophysis adenohypophysis increased distribution , abnormal
Show

 ZFA:0001345 interrenal gland interrenal gland increased size , abnormal
interrenal gland hyperplastic , abnormal
interrenal gland increased distribution , abnormal
Show

 ZFA:0009091 melanocyte melanocyte melanosome position , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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