ENSDARG00000037639


Danio rerio

Features
Gene ID: ENSDARG00000037639
  
Biological name :nkx3.2
  
Synonyms : NK3 homeobox 2 / nkx3.2
  
Possible biological names infered from orthology : Homeobox protein Nkx-3.2 / P78367 / P97503
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 212867
Gene end: 215051
  
Corresponding Affymetrix probe sets: Dr.21063.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000054821
NCBI entrez gene - 337865     See in Manteia.
swissprot - Q803Z6
ZFIN ID - ZDB-GENE-030127-1
Ensembl - ENSDARG00000037639
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NKX3-2ENSGALG00000031859Gallus gallus
 NKX3-2ENSG00000109705Homo sapiens
 Nkx3-2ENSMUSG00000049691Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nkx3.3 / NK3 homeobox 3ENSDARG0000006932741
hmx3a / H6 family homeobox 3a / HMX3* / P42581* / A6NHT5* / H6 family homeobox 3* / Homeobox protein HMX3 *ENSDARG0000007095531
nkx2.3 / NK2 homeobox 3 / Q8TAU0* / P42582* / P43688* / P52952* / P97334* / A6NCS4* / NKX2-5* / NKX2-6* / NK2 homeobox 5* / NK2 homeobox 6* / Homeobox protein Nkx-2.6 * / Homeobox protein N...ENSDARG0000003909530
nkx2.7 / NK2 transcription factor related 7 / Q8TAU0* / NKX2-6* / P42582* / P43688* / P52952* / P97334* / A6NCS4* / NKX2-3* / NKX2-5* / NK2 homeobox 3* / NK2 homeobox 5* / NK2 homeobox 6* /...ENSDARG0000002123229
nkx2.5 / NK2 homeobox 5 / Q8TAU0* / P42582* / P43688* / P52952* / P97334* / A6NCS4* / NKX2-3* / NKX2-6* / NK2 homeobox 3* / NK2 homeobox 6* / Homeobox protein Nkx-2.6 * / Homeobox protein N...ENSDARG0000001800428
nkx2.4a / NK2 homeobox 4aENSDARG0000007510728
nkx2.1 / NK2 homeobox 1 / Q9H2Z4* / P43699* / P50220* / Q9EQM3* / NKX2-4* / NK2 homeobox 4* / Homeobox protein Nkx-2.1 * / Homeobox protein Nkx-2.4 *ENSDARG0000001983527
Q90481 / nkx2.2a / NK2 homeobox 2a / NKX2-2* / O95096* / NK2 homeobox 2*ENSDARG0000005329827
hmx3b / H6 family homeobox 3bENSDARG0000009671627
nkx3-1 / NK3 homeobox 1 / P97436* / Q99801*ENSDARG0000007828026
hmx1 / H6 family homeobox 1 / O70218* / Q9NP08* / Homeobox protein HMX1 *ENSDARG0000009565126
nkx2.4b / NK2 homeobox 4bENSDARG0000010410725
hmx2 / H6 family homeobox 2 / A2RU54* / P43687* / Homeobox protein HMX2 *ENSDARG0000007095424
nkx2.2b / NK2 homeobox 2bENSDARG0000010154924
hmx4 / H6 family homeobox 4ENSDARG0000000794123


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001205 Meckel s cartilage Meckels cartilage malformed , abnormal
Meckels cartilage joint absent , abnormal
Show

 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage malformed , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage malformed , abnormal
ceratohyal cartilage joint absent , abnormal
Show

 ZFA:0001422 hyosymplectic cartilage hyosymplectic cartilage malformed , abnormal
Show

 ZFA:0001612 pharyngeal arch 1 pharyngeal arch 1 joint absent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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