Manteia

ENSDARG00000038672

Danio rerio

Features

Gene ID:	ENSDARG00000038672

Biological name :	tcf7

Synonyms :	tcf7 / transcription factor 7

Possible biological names infered from orthology :	P36402 / Q00417 / transcription factor 7, T cell specific

Species:	Danio rerio

Chr. number:	21
Strand:	1
Band:
Gene start:	45267589
Gene end:	45337118

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSDARP00000154649 Ensembl peptide - ENSDARP00000056473 Ensembl peptide - ENSDARP00000090271 Ensembl peptide - ENSDARP00000124154 Ensembl peptide - ENSDARP00000124703 Ensembl peptide - ENSDARP00000124981 Ensembl peptide - ENSDARP00000128252 Ensembl peptide - ENSDARP00000129238 Ensembl peptide - ENSDARP00000148615 swissprot - B3DIS1 swissprot - F1QZD5 swissprot - F1RAG0 swissprot - F8W2J8 swissprot - F8W4S5 swissprot - F8W5T7 swissprot - X1WDF3 swissprot - X1WG83 ZFIN ID - ZDB-GENE-050222-4 Ensembl - ENSDARG00000038672

See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
tcf7l2 / transcription factor 7 like 2 / Q924A0* / Q9NQB0* / transcription factor 7 like 2, T cell specific, HMG box*	ENSDARG00000004415	57
tcf7l1b / transcription factor 7 like 1b / Q9HCS4* / TCF7L1* / transcription factor 7 like 1*	ENSDARG00000007369	55
lef1 / lymphoid enhancer-binding factor 1 / P27782* / Q9UJU2*	ENSDARG00000031894	55
Q9YHE8 / tcf7l1a / transcription factor 7 like 1a / TCF7L1* / Q9HCS4* / transcription factor 7 like 1*	ENSDARG00000038159	55

Protein motifs (from Interpro)

Interpro ID	Name
IPR009071	High mobility group box domain
IPR013558	CTNNB1 binding, N-teminal
IPR024940	Transcription factor TCF/LEF
IPR027397	Catenin binding domain superfamily
IPR028785	Transcription factor 7

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006357	regulation of transcription by RNA polymerase II	IBA
biological_process	GO:0016055	Wnt signaling pathway	IEA
biological_process	GO:0021513	spinal cord dorsal/ventral patterning	IMP
biological_process	GO:0033153	T cell receptor V(D)J recombination	IEA
biological_process	GO:0033333	fin development	IMP
biological_process	GO:0033339	pectoral fin development	IMP
biological_process	GO:0060070	canonical Wnt signaling pathway	IEA
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0005667	transcription factor complex	IBA
molecular_function	GO:0003677	DNA binding	IEA
molecular_function	GO:0008013	beta-catenin binding	IBA
molecular_function	GO:0043565	sequence-specific DNA binding	IBA
molecular_function	GO:0044212	transcription regulatory region DNA binding	IBA

Pathways (from Reactome)

Pathway description

Formation of the beta-catenin:TCF transactivating complex

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0000008	brain	brain wholly posterioralized , abnormal	Show
ZFA:0000040	median fin fold	median fin fold decreased length , abnormal median fin fold undulate , abnormal	Show
ZFA:0000128	midbrain	midbrain morphology , abnormal	Show
ZFA:0000250	opercle	opercle shape , abnormal opercle increased width , abnormal	Show
ZFA:0000814	opercular lateral line neuromast	opercular lateral line neuromast premature , abnormal opercular lateral line neuromast mislocalised dorsally , abnormal	Show
ZFA:0001161	pectoral fin	pectoral fin decreased size , abnormal pectoral fin undulate , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr