ENSDARG00000039222


Danio rerio

Features
Gene ID: ENSDARG00000039222
  
Biological name :mpl
  
Synonyms : mpl / MPL proto-oncogene, thrombopoietin receptor
  
Possible biological names infered from orthology : P40238 / Q08351 / Thrombopoietin receptor
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 33949280
Gene end: 33980881
  
Corresponding Affymetrix probe sets: DrAffx.1.21.S1_at (Zebrafish Array)   NM_001003858_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000126229
Ensembl peptide - ENSDARP00000057296
Ensembl peptide - ENSDARP00000109739
NCBI entrez gene - 445381     See in Manteia.
RefSeq - XM_005166280
RefSeq - NM_001003858
RefSeq Peptide - NP_001003858
swissprot - F6NM07
swissprot - A8WHB2
swissprot - F1QDB2
swissprot - I3ITG5
ZFIN ID - ZDB-GENE-060421-1
Ensembl - ENSDARG00000039222
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MPLENSGALG00000009965Gallus gallus
 MPLENSG00000117400Homo sapiens
 MplENSMUSG00000006389Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
epor / erythropoietin receptor / P14753* / P19235*ENSDARG0000009083410


Protein motifs (from Interpro)
Interpro ID Name
 IPR003961  Fibronectin type III
 IPR013087  Zinc finger C2H2-type
 IPR013783  Immunoglobulin-like fold
 IPR015152  Growth hormone/erythropoietin receptor, ligand binding


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002574 thrombocyte differentiation IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003676 nucleic acid binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood decreased amount , abnormal
blood thrombocyte decreased amount , abnormal
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 ZFA:0000037 anatomical structure anatomical structure decreased amount , abnormal
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 ZFA:0000669 head kidney head kidney decreased amount , abnormal
head kidney thrombocyte decreased amount , abnormal
head kidney hematopoietic multipotent progenitor cell decreased amount , abnormal
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 ZFA:0009323 thrombocyte thrombocyte decreased amount , abnormal
thrombocyte cell proliferation decreased occurrence , abnormal
Show

 ZFA:0009351 thromboblast thromboblast cell proliferation decreased occurrence , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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