ENSDARG00000042642


Danio rerio

Features
Gene ID: ENSDARG00000042642
  
Biological name :wtap
  
Synonyms : Q7SXL7 / WT1 associated protein / wtap
  
Possible biological names infered from orthology : Q15007 / Q9ER69 / Wilms tumour 1-associating protein
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 30931414
Gene end: 30938246
  
Corresponding Affymetrix probe sets: Dr.6973.1.S1_at (Zebrafish Array)   NM_199853_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000062551
Ensembl peptide - ENSDARP00000119535
NCBI entrez gene - 334058     See in Manteia.
RefSeq - NM_199853
RefSeq Peptide - NP_956147
swissprot - Q5SPA6
swissprot - Q7SXL7
ZFIN ID - ZDB-GENE-030131-5990
Ensembl - ENSDARG00000042642
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 WTAPENSGALG00000011660Gallus gallus
 WTAPENSG00000146457Homo sapiens
 WtapENSMUSG00000060475Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR029732  WTAP/Mum2 family
 IPR033757  Pre-mRNA-splicing regulator WTAP


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000381 regulation of alternative mRNA splicing, via spliceosome ISS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0042981 regulation of apoptotic process IGI
 biological_processGO:0080009 mRNA methylation IBA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0016607 nuclear speck ISS
 cellular_componentGO:0036396 RNA N6-methyladenosine methyltransferase complex ISS


Pathways (from Reactome)
Pathway description
Processing of Capped Intron-Containing Pre-mRNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000135 notochord notochord curved ventral , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001261 ventricular system ventricular system decreased size , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000012827 F1R777 / mettl3 / methyltransferase like 3 / Q86U44*  / complex
 ENSDARG00000006816 gtf2f2b / general transcription factor IIF, polypeptide 2b / GTF2F2* / P13984* / Q8R0A0* / ral transcription factor IIF subunit 2 * / general transcription factor IIF subunit 2*  / reaction
 ENSDARG00000014898 ncbp2 / Q8JGR6 / nuclear cap binding protein subunit 2 / Q9CQ49* / NCBP2L* / P52298* / A6PVI3* / nuclear cap binding protein subunit 2 like*  / reaction
 ENSDARG00000069910 gtf2f2a / general transcription factor IIF, polypeptide 2a / GTF2F2* / P13984* / Q8R0A0* / ral transcription factor IIF subunit 2 * / general transcription factor IIF subunit 2*  / reaction
 ENSDARG00000070278 Q6NZ22 / mettl14 / methyltransferase like 14 / Q9HCE5* / Q3UIK4* / N6-adenosine-methyltransferase non-catalytic subunit *  / complex






 

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