ENSDARG00000014898


Danio rerio

Features
Gene ID: ENSDARG00000014898
  
Biological name :ncbp2
  
Synonyms : ncbp2 / nuclear cap binding protein subunit 2 / Q8JGR6
  
Possible biological names infered from orthology : A6PVI3 / NCBP2L / nuclear cap binding protein subunit 2 like / P52298 / Q9CQ49
  
Species: Danio rerio
  
Chr. number: 22
Strand: -1
Band:
Gene start: 38930725
Gene end: 38934989
  
Corresponding Affymetrix probe sets: Dr.13168.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000020688
swissprot - Q8JGR6
ZFIN ID - ZDB-GENE-020419-31
Ensembl - ENSDARG00000014898
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NCBP2ENSGALG00000006843Gallus gallus
 A6PVI3ENSG00000170935Homo sapiens
 NCBP2ENSG00000114503Homo sapiens
 Ncbp2ENSMUSG00000022774Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR027157  Nuclear cap-binding protein subunit 2
 IPR034148  NCBP2, RNA recognition motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
 biological_processGO:0000398 mRNA splicing, via spliceosome IBA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006408 snRNA export from nucleus ISS
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0008380 RNA splicing ISS
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0045292 mRNA cis splicing, via spliceosome IEA
 biological_processGO:0046833 positive regulation of RNA export from nucleus ISS
 biological_processGO:0051028 mRNA transport IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005846 nuclear cap binding complex IBA
 molecular_functionGO:0000339 RNA cap binding IBA
 molecular_functionGO:0000340 RNA 7-methylguanosine cap binding ISS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding ISS
 molecular_functionGO:0017069 snRNA binding ISS


Pathways (from Reactome)
Pathway description
Formation of the Early Elongation Complex
Transport of Mature mRNA derived from an Intron-Containing Transcript
RNA Polymerase II Pre-transcription Events
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
mRNA 3-end processing
Processing of Capped Intron-Containing Pre-mRNA
Processing of Intronless Pre-mRNAs
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain necrotic , abnormal
Show

 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
eye necrotic , abnormal
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 ZFA:0000112 gut gut hypoplastic , abnormal
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 ZFA:0000114 heart heart quality , abnormal
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 ZFA:0000123 liver liver hypoplastic , abnormal
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 ZFA:0001114 head head decreased size , abnormal
head necrotic , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000006816 gtf2f2b / general transcription factor IIF, polypeptide 2b / GTF2F2* / P13984* / Q8R0A0* / ral transcription factor IIF subunit 2 * / general transcription factor IIF subunit 2*  / complex
 ENSDARG00000018904 cstf3 / cleavage stimulation factor, 3 pre-RNA, subunit 3 / Q12996* / cleavage stimulation factor subunit 3*  / complex / reaction
 ENSDARG00000042724 supt5h / SPT5 homolog, DSIF elongation factor subunit / Supt5* / O55201* / O00267* / Transcription elongation factor SPT5 *  / complex / reaction
 ENSDARG00000044820 cstf1 / cleavage stimulation factor, 3 pre-RNA, subunit 1 / Q05048* / Q99LC2* / cleavage stimulation factor subunit 1*  / complex / reaction
 ENSDARG00000090788 cstf2 / cleavage stimulation factor, 3 pre-RNA, subunit 2 / P33240* / CSTF2T* / Q8C7E9* / Q9H0L4* / Q8BIQ5* / cleavage stimulation factor subunit 2* / cleavage stimulation factor subunit 2 ...  / complex / reaction
 ENSDARG00000113969 Q6DGQ0 / supt4h1 / SPT4 homolog, DSIF elongation factor subunit / P63272*  / complex / reaction
 ENSDARG00000017762 srrt / Q66I22 / serrate RNA effector molecule homolog (Arabidopsis) / Q99MR6* / Q9BXP5* / serrate, RNA effector molecule* / Serrate RNA effector molecule homolog *  / complex
 ENSDARG00000012827 F1R777 / mettl3 / methyltransferase like 3 / Q86U44*  / reaction
 ENSDARG00000017219 pabpc1a / poly(A) binding protein, cytoplasmic 1a / PABPC1* / Pabpc2* / PABPC3* / Pabpc6* / Q9H361* / P11940* / P29341* / Polyadenylate-binding protein 1 * / poly(A) binding protein cytopla...  / complex
 ENSDARG00000021140 pabpc1b / poly A binding protein, cytoplasmic 1 b / PABPC1* / Pabpc2* / PABPC3* / Pabpc6* / Q9H361* / P11940* / P29341* / Polyadenylate-binding protein 1 * / poly(A) binding protein cytopla...  / complex
 ENSDARG00000042642 wtap / Q7SXL7 / WT1 associated protein / Q9ER69* / Q15007* / Wilms tumour 1-associating protein*  / reaction
 ENSDARG00000069910 gtf2f2a / general transcription factor IIF, polypeptide 2a / GTF2F2* / P13984* / Q8R0A0* / ral transcription factor IIF subunit 2 * / general transcription factor IIF subunit 2*  / complex
 ENSDARG00000061411 nelfa / negative elongation factor complex member A / Q8BG30* / Q9H3P2* / Negative elongation factor A *  / complex / reaction
 ENSDARG00000070278 Q6NZ22 / mettl14 / methyltransferase like 14 / Q9HCE5* / Q3UIK4* / N6-adenosine-methyltransferase non-catalytic subunit *  / reaction
 ENSDARG00000004343 nelfe / negative elongation factor complex member E / P18615* / P19426* / negative elongation factor complex member E, Rdbp*  / complex / reaction






 

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