ENSDARG00000043665


Danio rerio

Features
Gene ID: ENSDARG00000043665
  
Biological name :glrx5
  
Synonyms : glrx5 / glutaredoxin 5 homolog (S. cerevisiae) / Q6PBM1
  
Possible biological names infered from orthology : glutaredoxin 5 / Glutaredoxin-related protein 5, mitochondrial / Q80Y14 / Q86SX6
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 10484015
Gene end: 10487951
  
Corresponding Affymetrix probe sets: Dr.311.1.S1_at (Zebrafish Array)   NM_213021_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000064111
NCBI entrez gene - 406294     See in Manteia.
RefSeq - NM_213021
RefSeq Peptide - NP_998186
swissprot - Q6PBM1
ZFIN ID - ZDB-GENE-040426-1957
Ensembl - ENSDARG00000043665
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GLRX5ENSGALG00000011079Gallus gallus
 GLRX5ENSG00000182512Homo sapiens
 Glrx5ENSMUSG00000021102Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002109  Glutaredoxin
 IPR004480  Monothiol glutaredoxin-related
 IPR012336  Thioredoxin-like fold
 IPR014434  Monothiol glutaredoxin
 IPR033658  Glutaredoxin, PICOT-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016226 iron-sulfur cluster assembly IMP
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion IDA
 molecular_functionGO:0009055 electron transfer activity IEA
 molecular_functionGO:0015035 protein disulfide oxidoreductase activity IEA
 molecular_functionGO:0015036 disulfide oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051537 2 iron, 2 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Mitochondrial iron-sulfur cluster biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood quality , abnormal
Show

 ZFA:0001094 whole organism whole organism viability , abnormal
Show

 ZFA:0009044 blood cell blood cell low saturation , abnormal
Show

 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte decreased amount , abnormal
nucleate erythrocyte low saturation , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000043665 glrx5 / Q6PBM1 / glutaredoxin 5 homolog (S. cerevisiae) / Q86SX6* / Q80Y14* / glutaredoxin 5* / Glutaredoxin-related protein 5, mitochondrial *  / reaction
 ENSDARG00000051956 isca1 / Q4QRC6 / iron-sulfur cluster assembly 1 / Q9BUE6*  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr