ENSDARG00000044153


Danio rerio

Features
Gene ID: ENSDARG00000044153
  
Biological name :ppp1cb
  
Synonyms : ppp1cb / protein phosphatase 1, catalytic subunit, beta isozyme
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 25635953
Gene end: 25649079
  
Corresponding Affymetrix probe sets: Dr.25291.3.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000109442
NCBI entrez gene - 100003223     See in Manteia.
RefSeq - NM_001004527
RefSeq Peptide - NP_001004527
swissprot - F1QI59
ZFIN ID - ZDB-GENE-030616-609
Ensembl - ENSDARG00000044153
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ppp1caa / protein phosphatase 1, catalytic subunit, alpha isozyme a / P62137* / PPP1CA* / P62136* / protein phosphatase 1 catalytic subunit alpha* / protein phosphatase 1, catalytic subunit...ENSDARG0000000348684
PPP1CC / protein phosphatase 1 catalytic subunit gamma / P36873*ENSDARG0000009922684
ppp1cab / protein phosphatase 1, catalytic subunit, alpha isozyme b / PPP1CC* / P36873* / P63087* / protein phosphatase 1 catalytic subunit gamma* / Serine/threonine-protein phosphatase PP1...ENSDARG0000007156683
ppp1cbl / protein phosphatase 1, catalytic subunit, beta isoform, likeENSDARG0000010201269


Protein motifs (from Interpro)
Interpro ID Name
 IPR004843  Calcineurin-like phosphoesterase domain, ApaH type
 IPR006186  Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
 IPR029052  Metallo-dependent phosphatase-like
 IPR031675  Serine-threonine protein phosphatase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IMP
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0060028 convergent extension involved in axis elongation IMP
 cellular_componentGO:0000164 protein phosphatase type 1 complex IEA
 cellular_componentGO:0072357 PTW/PP1 phosphatase complex IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000123 liver liver decreased size , abnormal
liver aplastic , abnormal
Show

 ZFA:0000135 notochord notochord increased width , abnormal
notochord shortened , abnormal
notochord mesodermal cell positional polarity , abnormal
Show

 ZFA:0000279 segmental plate segmental plate increased width , abnormal
segmental plate shortened , abnormal
segmental plate mesodermal cell positional polarity , abnormal
Show

 ZFA:0001094 whole organism whole organism anterior-posterior axis decreased length , abnormal
whole organism anterior-posterior axis shortened , abnormal
whole organism anterior-posterior axis curved , abnormal
Show

 ZFA:0009138 mesodermal cell mesodermal cell has extra parts of type mesodermal cell bleb, abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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