ENSDARG00000071566


Danio rerio

Features
Gene ID: ENSDARG00000071566
  
Biological name :ppp1cab
  
Synonyms : ppp1cab / protein phosphatase 1, catalytic subunit, alpha isozyme b
  
Possible biological names infered from orthology : P36873 / P63087 / PPP1CC / protein phosphatase 1 catalytic subunit gamma / Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 13205955
Gene end: 13223449
  
Corresponding Affymetrix probe sets: Dr.3477.1.S1_at (Zebrafish Array)   NM_212710_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000087338
NCBI entrez gene - 327301     See in Manteia.
RefSeq - NM_212710
RefSeq Peptide - NP_997875
swissprot - Q7ZVR3
ZFIN ID - ZDB-GENE-030131-5512
Ensembl - ENSDARG00000071566
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PPP1CCENSGALG00000004571Gallus gallus
 P36873ENSG00000186298Homo sapiens
 P63087ENSMUSG00000004455Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ppp1caa / protein phosphatase 1, catalytic subunit, alpha isozyme a / P62137* / PPP1CA* / P62136* / protein phosphatase 1 catalytic subunit alpha* / protein phosphatase 1, catalytic subunit...ENSDARG0000000348694
PPP1CC / protein phosphatase 1 catalytic subunit gamma / P36873*ENSDARG0000009922689
ppp1cb / protein phosphatase 1, catalytic subunit, beta isozymeENSDARG0000004415382
ppp1cbl / protein phosphatase 1, catalytic subunit, beta isoform, likeENSDARG0000010201263


Protein motifs (from Interpro)
Interpro ID Name
 IPR004843  Calcineurin-like phosphoesterase domain, ApaH type
 IPR006186  Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
 IPR029052  Metallo-dependent phosphatase-like
 IPR031675  Serine-threonine protein phosphatase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0006470 protein dephosphorylation IEA
 cellular_componentGO:0000164 protein phosphatase type 1 complex IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain distended , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000084 yolk yolk edematous , abnormal
Show

 ZFA:0001094 whole organism whole organism malformed , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel decreased functionality , abnormal
intersegmental vessel dilated , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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