ENSDARG00000044688
Danio rerio phosphatase dusp4 activity protein domain tyrosine dual specificity protein-tyrosine mapk dephosphorylation catalytic map kinase endoderm serine threonine specific phosphatases rhodanese-like mitogen-activated active site phosphatase-like inactivation formation endodermal cell fate specification peptidyl-tyrosine
Features Gene ID: ENSDARG00000044688 Biological name :dusp4 Synonyms : dual specificity phosphatase 4 / dusp4 Possible biological names infered from orthology : Dual specificity protein phosphatase 4 / Q13115 / Q8BFV3 Species: Danio rerio Chr. number: 21 Strand: -1 Band: Gene start: 20113470 Gene end: 20120543 Corresponding Affymetrix probe sets: Dr.9304.1.S1_at (Zebrafish Array) NM_201171_at (Zebrafish Genome Array with custom cdf files) Cross references: Ensembl peptide - ENSDARP00000065663 NCBI entrez gene - 394146
See in Manteia .
RefSeq - NM_201171 RefSeq Peptide - NP_957465 swissprot - Q7SZF3 ZFIN ID - ZDB-GENE-040426-709 Ensembl - ENSDARG00000044688
See expression report in BioGPS See gene description in Wikigenes See co-cited genes in PubMed Ortholog prediction (from Ensembl )
Paralog prediction (from Ensembl ) dusp1 / dual specificity phosphatase 1 / P28562* / P28563* / Dual specificity protein phosphatase 1 * ENSDARG00000100515 58 dusp5 / dual specificity phosphatase 5 / Q16690* ENSDARG00000019307 43 dusp2 / dual specificity phosphatase 2 / Q05923* ENSDARG00000098108 42 dusp8a / dual specificity phosphatase 8a / DUSP8* / Q13202* / O09112* / dual specificity phosphatase 8* / Dual specificity protein phosphatase 8 * ENSDARG00000009299 33 dusp7 / dual specificity phosphatase 7 / Q16829* ENSDARG00000101413 31 dusp16 / dual specificity phosphatase 16 / Q9BY84* ENSDARG00000102474 31 dusp6 / dual specificity phosphatase 6 / Q16828* / Q9DBB1* / Dual specificity protein phosphatase 6 * ENSDARG00000070914 30 dusp10 / dual specificity phosphatase 10 / Q9ESS0* / Q9Y6W6* / Dual specificity protein phosphatase 10 * ENSDARG00000052465 28 si:dkey-175m17.7 ENSDARG00000078317 24 ssh2b / slingshot protein phosphatase 2b / SSH2* / Q5SW75* / Q76I76* / slingshot protein phosphatase 2* / Protein phosphatase Slingshot homolog 2 * ENSDARG00000098955 24 ssh2a / slingshot protein phosphatase 2a / SSH2* / Q5SW75* / Q76I76* / slingshot protein phosphatase 2* / Protein phosphatase Slingshot homolog 2 * ENSDARG00000088440 23 ssh1a / slingshot protein phosphatase 1a / SSH1* / Q76I79* / Q8WYL5* / slingshot protein phosphatase 1* / Protein phosphatase Slingshot homolog 1 * ENSDARG00000056780 21 si:ch211-203d1.3 / SSH3* / Q8TE77* / Q8K330* / slingshot protein phosphatase 3* / Mus musculus slingshot protein phosphatase 3 (Ssh3), transcript variant 2, mRNA.* ENSDARG00000079591 21 ssh1b / slingshot protein phosphatase 1b / SSH1* / Q76I79* / Q8WYL5* / slingshot protein phosphatase 1* / Protein phosphatase Slingshot homolog 1 * ENSDARG00000010031 19 si:ch211-195b15.8 ENSDARG00000094836 18
Protein motifs (from Interpro ) IPR000340 Dual specificity phosphatase, catalytic domain IPR000387 Tyrosine specific protein phosphatases domain IPR001763 Rhodanese-like domain IPR003595 Protein-tyrosine phosphatase, catalytic IPR008343 Mitogen-activated protein (MAP) kinase phosphatase IPR016130 Protein-tyrosine phosphatase, active site IPR020422 Dual specificity protein phosphatase domain IPR024950 Dual specificity phosphatase IPR029021 Protein-tyrosine phosphatase-like
Gene Ontology (GO ) nitrogen compound metabolic process cell communication cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process cellular response to stimulus anatomical structure development cellular developmental process nitrogen compound metabolic process cell communication cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process cellular response to stimulus anatomical structure development cellular developmental process nitrogen compound metabolic process cell communication cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process cellular response to stimulus anatomical structure development cellular developmental process nitrogen compound metabolic process cell communication cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process cellular response to stimulus anatomical structure development cellular developmental process nitrogen compound metabolic process cell communication cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process cellular response to stimulus anatomical structure development cellular developmental process nitrogen compound metabolic process cell communication cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process cellular response to stimulus anatomical structure development cellular developmental process nitrogen compound metabolic process cell communication cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process cellular response to stimulus anatomical structure development cellular developmental process nitrogen compound metabolic process cell communication cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process cellular response to stimulus anatomical structure development cellular developmental process nitrogen compound metabolic process cell communication cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process cellular response to stimulus anatomical structure development cellular developmental process nitrogen compound metabolic process cell communication cellular metabolic process primary metabolic process regulation of molecular function organic substance metabolic process cellular response to stimulus anatomical structure development cellular developmental process nitrogen compounitrogen compound metabolic process cell communicatcell communication cellular metabocellular metabolic process primary metabolprimary metabolic process regulation of mregulation of molecular function organic substanorganic substance metabolic process cellular responcellular response to stimulus anatomical struanatomical structure development cellular develocellular developmental process catalytic activity, acting on a protein hydrolase activity catalytic activity, acting on a protein hydrolase activity catalytic activity, acting on a protein hydrolase activity catalytic activity, acting on a protein hydrolase activity catalytic activity, acting on a protein hydrolase activity catalytic activity, acting on a protein hydrolase activity catalytic activity, acting on a protein hydrolase activity catalytic activity, acting on a protein hydrolase activity catalytic activity, acting on a protein hydrolase activity catalytic activity, acting on a protein hydrolase activity catalytic activity, acting on a proteincatalytic activity, acting on a protein hydrolase activityhydrolase activity
Pathways (from Reactome )
Phenotype (from MGI , Zfin or HPO ) ZFA:0000017 endoderm endoderm morphology , abnormal
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ZFA:0000112 gut gut morphology , abnormal
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ZFA:0001094 whole organism whole organism decreased length , abnormal
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ZFA:0001114 head head decreased size , abnormal head necrotic , abnormal
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ZFA:0001390 pancreatic bud pancreatic bud morphology , abnormal
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Interacting proteins (from Reactome ) ENSDARG00000023110 mapk7 / mitogen-activated protein kinase 7 / Q13164* / Q9WVS8* / reaction ENSDARG00000027552 mapk1 / mitogen-activated protein kinase 1 / P28482* / P63085* / Mus musculus mitogen-activated protein kinase 1 (Mapk1), transcript variant 3, mRNA.* / reaction ENSDARG00000070573 mapk3 / mitogen-activated protein kinase 3 / P27361* / Q63844* / reaction
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