ENSDARG00000045641


Danio rerio

Features
Gene ID: ENSDARG00000045641
  
Biological name :usp3
  
Synonyms : ubiquitin specific peptidase 3 / usp3
  
Possible biological names infered from orthology : Q91W36 / Q9Y6I4
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 26738450
Gene end: 26753196
  
Corresponding Affymetrix probe sets: Dr.6883.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000129176
NCBI entrez gene - 569679     See in Manteia.
RefSeq - NM_001199871
RefSeq Peptide - NP_001186800
swissprot - X1WG21
ZFIN ID - ZDB-GENE-030131-5142
Ensembl - ENSDARG00000045641
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 USP3ENSGALG00000003427Gallus gallus
 USP3ENSG00000140455Homo sapiens
 Usp3ENSMUSG00000032376Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
usp44 / ubiquitin specific peptidase 44 / Q9H0E7*ENSDARG0000008986133
usp49 / ubiquitin specific peptidase 49 / Q6P9L4* / Q70CQ1*ENSDARG0000000022931
usp22 / A6H8I0 / ubiquitin specific peptidase 22 / USP51* / Q70EK9* / Q8CEG8* / Q9UPT9* / B1AY15* / Q5DU02* / A6NNY8* / USP27X* / ubiquitin specific protease 51* / ubiquitin specific peptid...ENSDARG0000004040726
usp36 / ubiquitin specific peptidase 36 / B1AQJ2* / Q9P275*ENSDARG0000003232721
usp42 / ubiquitin specific peptidase 42 / B2RQC2* / Q9H9J4*ENSDARG0000007730021


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR001607  Zinc finger, UBP-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016579 protein deubiquitination IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000155 somite somite fused with somite , abnormal
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 ZFA:0000445 optic tectum optic tectum increased size , abnormal
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 ZFA:0001094 whole organism whole organism decreased size , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001115 trunk trunk decreased thickness , abnormal
trunk bent , abnormal
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 ZFA:0001117 post-vent region post-vent region curled , abnormal
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 ZFA:0001604 caudal fin upper lobe caudal fin upper lobe fused with caudal fin lower lobe , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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