ENSDARG00000045789


Danio rerio

Features
Gene ID: ENSDARG00000045789
  
Biological name :srgap1b
  
Synonyms : SLIT-ROBO Rho GTPase activating protein 1b / srgap1b
  
Possible biological names infered from orthology : Q7Z6B7 / Q91Z69 / SLIT-ROBO Rho GTPase activating protein 1 / SRGAP1
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 9279515
Gene end: 9335035
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000014410
Ensembl peptide - ENSDARP00000048706
NCBI entrez gene - 555788     See in Manteia.
swissprot - B7ZVG9
swissprot - Q5RIG8
ZFIN ID - ZDB-GENE-041210-103
Ensembl - ENSDARG00000045789
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SRGAP1ENSGALG00000009825Gallus gallus
 Q7Z6B7ENSG00000196935Homo sapiens
 Q91Z69ENSMUSG00000020121Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
srgap1a / SLIT-ROBO Rho GTPase activating protein 1a / Q7Z6B7* / Q91Z69* / SRGAP1* / SLIT-ROBO Rho GTPase activating protein 1*ENSDARG0000000746171
srgap3 / SLIT-ROBO Rho GTPase activating protein 3 / O43295*ENSDARG0000006030958
B0S6J3 / srgap2 / SLIT-ROBO Rho GTPase activating protein 2 / O75044* / Q91Z67* / P0DJJ0* / P0DMP2* / SRGAP2C* / SRGAP2B* / SLIT-ROBO Rho GTPase activating protein 2B* / SLIT-ROBO Rho GTPas...ENSDARG0000003216157
arhgap4b / Rho GTPase activating protein 4b / P98171* / ARHGAP4* / Rho GTPase activating protein 4*ENSDARG0000001500338
arhgap4a / Rho GTPase activating protein 4a / P98171* / ARHGAP4* / Rho GTPase activating protein 4*ENSDARG0000003926532
arhgap17a / Rho GTPase activating protein 17a / Q68EM7* / ARHGAP17* / Rho GTPase activating protein 17*ENSDARG0000002048813
ARHGAP22 / si:dkey-191m6.4 / Q7Z5H3* / Q8BL80* / Rho GTPase activating protein 22*ENSDARG0000007643412
si:ch211-114m9.1 / Q17R89* / ARHGAP44* / Rho GTPase activating protein 44*ENSDARG0000010242412
arhgap24 / Rho GTPase activating protein 24 / Q8C4V1* / Q8N264*ENSDARG0000010097311
arhgap44 / Rho GTPase activating protein 44 / Q17R89* / Q5SSM3*ENSDARG0000010454911
arhgap25 / Rho GTPase activating protein 25 / P42331* / Q8BYW1*ENSDARG000000617849
arhgap17b / Rho GTPase activating protein 17b / Q3UIA2* / Q68EM7* / ARHGAP17* / Rho GTPase activating protein 17*ENSDARG000000622639
sh3bp1 / SH3-domain binding protein 1 / Q9Y3L3* / P55194* / Z83844.3* / AL592169.1*ENSDARG000000781199
si:ch211-247j9.1ENSDARG000000792838
arhgap22 / Rho GTPase activating protein 22ENSDARG000000212556


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001060  FCH domain
 IPR001452  SH3 domain
 IPR008936  Rho GTPase activation protein
 IPR027267  AH/BAR domain superfamily
 IPR031160  F-BAR domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0030336 negative regulation of cell migration IBA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0048365 Rac GTPase binding IBA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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