ENSDARG00000045946


Danio rerio

Features
Gene ID: ENSDARG00000045946
  
Biological name :sec24d
  
Synonyms : sec24d / SEC24 homolog D, COPII coat complex component
  
Possible biological names infered from orthology : O94855 / Sec24 related gene family, member D (S. cerevisiae)
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 69905307
Gene end: 69951096
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000035564
NCBI entrez gene - 553407     See in Manteia.
swissprot - F1QRB4
ZFIN ID - ZDB-GENE-070117-2501
Ensembl - ENSDARG00000045946
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SEC24DENSGALG00000011998Gallus gallus
 O94855ENSG00000150961Homo sapiens
 Sec24dENSMUSG00000039234Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sec24c / SEC24 homolog C, COPII coat complex component / P53992* / Sec24 related gene family, member C (S. cerevisiae)*ENSDARG0000010351658
sec24b / SEC24 homolog B, COPII coat complex component / O95487* / Sec24 related gene family, member B (S. cerevisiae)*ENSDARG0000007190626
sec24a / SEC24 homolog A, COPII coat complex component / O95486*ENSDARG0000010437523
si:dkey-13n15.2ENSDARG0000006180611


Protein motifs (from Interpro)
Interpro ID Name
 IPR002035  von Willebrand factor, type A
 IPR006895  Zinc finger, Sec23/Sec24-type
 IPR006896  Sec23/Sec24, trunk domain
 IPR006900  Sec23/Sec24, helical domain
 IPR007123  Gelsolin-like domain
 IPR012990  Sec23/Sec24 beta-sandwich
 IPR029006  ADF-H/Gelsolin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 biological_processGO:0060536 cartilage morphogenesis IMP
 biological_processGO:0070278 extracellular matrix constituent secretion IMP
 cellular_componentGO:0030127 COPII vesicle coat IEA
 molecular_functionGO:0008270 zinc ion binding IEA


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport
MHC class II antigen presentation
Cargo concentration in the ER
Antigen Presentation: Folding, assembly and peptide loading of class I MHC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000257 pectoral fin cartilage pectoral fin cartilage malformed , abnormal
Show

 ZFA:0000282 sensory system sensory system quality , abnormal
Show

 ZFA:0000292 surface structure surface structure quality , abnormal
Show

 ZFA:0000431 semicircular canal semicircular canal aplastic , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
Show

 ZFA:0001114 head head decreased length , abnormal
Show

 ZFA:0001161 pectoral fin pectoral fin quality , abnormal
pectoral fin kinked , abnormal
pectoral fin decreased length , abnormal
pectoral fin degenerate , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage decreased length , abnormal
Meckels cartilage cell-cell adherens junction increased amount , abnormal
Meckels cartilage chondrocyte length , abnormal
Meckels cartilage chondrocyte disorganized , abnormal
Meckels cartilage chondrocyte obtuse , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage malformed , abnormal
ceratohyal cartilage chondrocyte obtuse , abnormal
Show

 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage physical object quality , abnormal
pharyngeal arch cartilage chondrocyte malformed , abnormal
pharyngeal arch cartilage chondrocyte disorganized , abnormal
pharyngeal arch cartilage decreased size , abnormal
pharyngeal arch cartilage extracellular matrix decreased volume , abnormal
pharyngeal arch cartilage immature , abnormal
Show

 ZFA:0001500 auditory capsule auditory capsule malformed , abnormal
Show

 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage decreased size , abnormal
Show

 ZFA:0009084 chondrocyte chondrocyte malformed , abnormal
chondrocyte actin filament disorganized , abnormal
chondrocyte cell-cell adherens junction increased amount , abnormal
chondrocyte undifferentiated , abnormal
chondrocyte endoplasmic reticulum lumen swollen , abnormal
chondrocyte Golgi apparatus decreased size , abnormal
chondrocyte Golgi apparatus disorganized , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr