ENSDARG00000051874


Danio rerio

Features
Gene ID: ENSDARG00000051874
  
Biological name :stra6
  
Synonyms : F1RAX4 / stimulated by retinoic acid 6 / stra6
  
Possible biological names infered from orthology : Q9BX79 / stimulated by retinoic acid gene 6
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 22571475
Gene end: 22634675
  
Corresponding Affymetrix probe sets: Dr.5258.1.A1_at (Zebrafish Array)   NM_001045312_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000067478
Ensembl peptide - ENSDARP00000126450
Ensembl peptide - ENSDARP00000131530
NCBI entrez gene - 724007     See in Manteia.
RefSeq - NM_001045312
RefSeq - XM_005170689
RefSeq - XM_021470528
RefSeq Peptide - NP_001038777
swissprot - F1RAX4
ZFIN ID - ZDB-GENE-060616-252
Ensembl - ENSDARG00000051874
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 STRA6ENSGALG00000001449Gallus gallus
 STRA6ENSG00000137868Homo sapiens
 Stra6ENSMUSG00000032327Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
stra6l / STRA6-like / Q9DBN1* / Stimulated by retinoic acid 6 protein-like *ENSDARG0000006246719


Protein motifs (from Interpro)
Interpro ID Name
 IPR026612  Receptor for retinol uptake STRA6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0034633 retinol transport IDA
 biological_processGO:0035461 vitamin transmembrane transport IEA
 biological_processGO:0043009 chordate embryonic development IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005516 calmodulin binding IDA
 molecular_functionGO:0016918 retinal binding IEA
 molecular_functionGO:0019841 retinol binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0090482 vitamin transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
The canonical retinoid cycle in rods (twilight vision)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000114 heart heart morphology , abnormal
heart malformed , abnormal
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 ZFA:0000471 atrium atrium dilated , abnormal
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 ZFA:0001071 presumptive neural retina presumptive neural retina decreased size , abnormal
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 ZFA:0001094 whole organism whole organism curved ventral , abnormal
whole organism increased curvature , abnormal
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 ZFA:0001114 head head hemorrhagic , abnormal
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 ZFA:0001205 Meckel s cartilage Meckels cartilage deformed , abnormal
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 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage deformed , abnormal
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 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage deformed , abnormal
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 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage decreased size , abnormal
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 ZFA:0001613 pharyngeal arch 3-7 pharyngeal arch 3-7 morphology , abnormal
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 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte position , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000037191 ttr / transthyretin (prealbumin, amyloidosis type I) / P02766* / P07309* / transthyretin*  / complex / reaction
 ENSDARG00000101199 rbp4 / retinol binding protein 4, plasma / P02753* / Q00724* / retinol binding protein 4*  / complex / reaction






 

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