ENSDARG00000051880


Danio rerio

Features
Gene ID: ENSDARG00000051880
  
Biological name :kcnj11
  
Synonyms : kcnj11 / potassium inwardly-rectifying channel, subfamily J, member 11
  
Possible biological names infered from orthology : ATP-sensitive inward rectifier potassium channel 11 / potassium voltage-gated channel subfamily J member 11 / Q14654 / Q61743
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 22853718
Gene end: 22854863
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000068078
NCBI entrez gene - 664687     See in Manteia.
RefSeq - NM_001039827
RefSeq Peptide - NP_001034916
swissprot - Q2HX26
ZFIN ID - ZDB-GENE-060308-2
Ensembl - ENSDARG00000051880
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KCNJ11ENSGALG00000020505Gallus gallus
 KCNJ11ENSG00000187486Homo sapiens
 Kcnj11ENSMUSG00000096146Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
kcnj8 / potassium inwardly-rectifying channel, subfamily J, member 8 / P97794* / Q15842* / potassium voltage-gated channel subfamily J member 8*ENSDARG0000004558966
kcnj11l / potassium inwardly-rectifying channel, subfamily J, member 11, likeENSDARG0000003143865
zgc:162160ENSDARG0000006025945
kcnj9 / potassium inwardly-rectifying channel, subfamily J, member 9 / P48543* / Q92806* / potassium voltage-gated channel subfamily J member 9*ENSDARG0000006163644
kcnj12a / potassium inwardly-rectifying channel, subfamily J, member 12a / KCNJ18* / P52187* / Q14500* / B7U540* / KCNJ12* / ATP-sensitive inward rectifier potassium channel 12 * / potassiu...ENSDARG0000010496544
kcnj5 / potassium inwardly-rectifying channel, subfamily J, member 5 / P48544* / P48545* / potassium voltage-gated channel subfamily J member 5* / G protein-activated inward rectifier potas...ENSDARG0000006101443
kcnj3b / potassium inwardly-rectifying channel, subfamily J, member 3b / KCNJ3* / P48549* / P63250* / potassium voltage-gated channel subfamily J member 3* / G protein-activated inward rect...ENSDARG0000006221743
kcnj12b / potassium inwardly-rectifying channel, subfamily J, member 12bENSDARG0000006261843
kcnj3a / potassium inwardly-rectifying channel, subfamily J, member 3a / KCNJ3* / P48549* / P63250* / potassium voltage-gated channel subfamily J member 3* / G protein-activated inward rect...ENSDARG0000007716543
kcnj2a / potassium inwardly-rectifying channel, subfamily J, member 2a / KCNJ2* / P63252* / P35561* / potassium voltage-gated channel subfamily J member 2* / potassium inwardly-rectifying c...ENSDARG0000001941842
KCNJ6 / potassium voltage-gated channel subfamily J member 6 / P48051*ENSDARG0000005898542
kcnj19a / potassium voltage-gated channel subfamily J member 19aENSDARG0000005974742
kcnj19b / potassium voltage-gated channel, subfamily J, member 19bENSDARG0000006267242
CABZ01079818.1 / KCNJ4* / P48050* / potassium voltage-gated channel subfamily J member 4*ENSDARG0000006811042
kcnj14 / potassium inwardly-rectifying channel, subfamily J, member 14 / Q8JZN3* / Q9UNX9* / ATP-sensitive inward rectifier potassium channel 14 * / potassium voltage-gated channel subfamil...ENSDARG0000007591442
kcnj2b / potassium inwardly-rectifying channel, subfamily J, member 2b / KCNJ2* / P63252* / P35561* / potassium voltage-gated channel subfamily J member 2* / potassium inwardly-rectifying c...ENSDARG0000010438941
si:ch211-113j13.2ENSDARG0000004070136
kcnj1b / potassium inwardly-rectifying channel, subfamily J, member 1b / KCNJ1* / O88335* / P48048* / ATP-sensitive inward rectifier potassium channel 1 * / potassium voltage-gated channel ...ENSDARG0000000266633
kcnj1a.6 / potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6 / KCNJ1* / O88335* / P48048* / ATP-sensitive inward rectifier potassium channel 1 * / potassium ...ENSDARG0000008848432
kcnj10a / potassium inwardly-rectifying channel, subfamily J, member 10a / Q9JM63* / KCNJ10* / P78508* / ATP-sensitive inward rectifier potassium channel 10 * / potassium voltage-gated chan...ENSDARG0000009081532


Protein motifs (from Interpro)
Interpro ID Name
 IPR003279  Potassium channel, inwardly rectifying, Kir6.2
 IPR013518  Potassium channel, inwardly rectifying, Kir, cytoplasmic
 IPR014756  Immunoglobulin E-set
 IPR016449  Potassium channel, inwardly rectifying, Kir


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003323 type B pancreatic cell development IMP
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0010107 potassium ion import IBA
 biological_processGO:0031018 endocrine pancreas development IMP
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005242 inward rectifier potassium channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0015272 ATP-activated inward rectifier potassium channel activity IEA


Pathways (from Reactome)
Pathway description
ATP sensitive Potassium channels
ABC-family proteins mediated transport
Regulation of insulin secretion
Ion homeostasis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001260 endocrine pancreas endocrine pancreas increased distribution , abnormal
Show

 ZFA:0009102 pancreatic B cell pancreatic B cell increased amount , abnormal
pancreatic B cell decreased amount , abnormal
pancreatic B cell decreased area , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000015985 abcc9 / ATP-binding cassette, sub-family C (CFTR/MRP), member 9 / O60706* / P70170* / ATP binding cassette subfamily C member 9*  / complex
 ENSDARG00000051880 kcnj11 / potassium inwardly-rectifying channel, subfamily J, member 11 / Q14654* / Q61743* / ATP-sensitive inward rectifier potassium channel 11 * / potassium voltage-gated channel subfamil...  / complex
 ENSDARG00000045589 kcnj8 / potassium inwardly-rectifying channel, subfamily J, member 8 / P97794* / Q15842* / potassium voltage-gated channel subfamily J member 8*  / complex






 

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