ENSDARG00000051896


Danio rerio

Features
Gene ID: ENSDARG00000051896
  
Biological name :fbn2a
  
Synonyms : fbn2a / fibrillin 2a
  
Possible biological names infered from orthology : FBN1 / FBN2 / fibrillin 1 / Fibrillin-1 Asprosin / fibrillin 2 / Fibrillin-2 Fibrillin-2 C-terminal peptide / P35555 / P35556 / Q61554 / Q61555
  
Species: Danio rerio
  
Chr. number: 10
Strand: -1
Band:
Gene start: 16313851
Gene end: 16474216
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000068094
Ensembl peptide - ENSDARP00000123990
swissprot - F1QNG9
swissprot - F8W453
ZFIN ID - ZDB-GENE-090112-4
Ensembl - ENSDARG00000051896
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FBN1ENSGALG00000004960Gallus gallus
 FBN2ENSGALG00000014686Gallus gallus
 FBN1ENSG00000166147Homo sapiens
 FBN2ENSG00000138829Homo sapiens
 Fbn1ENSMUSG00000027204Mus musculus
 Fbn2ENSMUSG00000024598Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fbn2b / fibrillin 2bENSDARG0000009823764
si:dkey-30j22.1ENSDARG0000004282937
si:ch73-105b23.1ENSDARG0000008755818
BX663503.3 / LTBP4* / Q8K4G1* / Q8N2S1* / latent transforming growth factor beta binding protein 4*ENSDARG0000009913715
ltbp1 / latent transforming growth factor beta binding protein 1 / Q14766* / Q8CG19*ENSDARG0000005692214
FP102018.1 / Danio rerio latent transforming growth factor beta binding protein 3 (ltbp3), mRNA. / LTBP3* / Q9NS15* / latent transforming growth factor beta binding protein 3*ENSDARG0000003568213
fbln2 / fibulin 2 / P37889* / P98095*ENSDARG0000001515610
si:dkey-235d18.5ENSDARG000000396529
FBLN1 / fibulin 1 / P23142*ENSDARG000001033116
efemp2b / EGF containing fibulin extracellular matrix protein 2b / EFEMP2* / O95967* / Q9WVJ9* / EGF containing fibulin extracellular matrix protein 2* / EGF-containing fibulin-like extrace...ENSDARG000000208114
fbln5 / fibulin 5 / Q9UBX5* / Q9WVH9*ENSDARG000000392734
efemp2a / EGF containing fibulin extracellular matrix protein 2a / EFEMP2* / O95967* / Q9WVJ9* / EGF containing fibulin extracellular matrix protein 2* / EGF-containing fibulin-like extrace...ENSDARG000000943244
CU570800.1 / EFEMP1* / Q12805* / EGF containing fibulin extracellular matrix protein 1*ENSDARG000000591213
si:ch73-173h19.3 / EFEMP1* / Q12805* / Q8BPB5* / EGF containing fibulin extracellular matrix protein 1* / EGF-containing fibulin-like extracellular matrix protein 1 *ENSDARG000001042103


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR017878  TB domain
 IPR018097  EGF-like calcium-binding, conserved site
 IPR026823  Complement Clr-like EGF domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0090287 regulation of cellular response to growth factor stimulus IBA
 cellular_componentGO:0031012 extracellular matrix IBA
 molecular_functionGO:0005201 extracellular matrix structural constituent IBA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix
Elastic fibre formation
Molecules associated with elastic fibres
Integrin cell surface interactions
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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