ENSDARG00000052703


Danio rerio
membranecisd2ironautophagybindingmitochondrionendoplasmicreticulumclustersulphur-containingdomaincdgsh-typesulphurdomain-containingmitoneetn-terminalmulticellularorganismagingregulationmitochondrialouterintegralcomponentintracellularmembrane-boundedorganelleproteinhomodimerizationactivitymetal

Features
Gene ID: ENSDARG00000052703
  
Biological name :cisd2
  
Synonyms : CDGSH iron sulfur domain 2 / cisd2 / Q7T326
  
Possible biological names infered from orthology : CDGSH iron-sulfur domain-containing protein 2 / Q8N5K1 / Q9CQB5
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 43686251
Gene end: 43692141
  
Corresponding Affymetrix probe sets: Dr.26471.1.S1_at (Zebrafish Array)   NM_200383_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000069092
Ensembl peptide - ENSDARP00000122608
NCBI entrez gene - 393354     See in Manteia.
RefSeq - NM_200383
RefSeq Peptide - NP_956677
swissprot - Q7T326
swissprot - Z4YJ68
ZFIN ID - ZDB-GENE-040426-1381
Ensembl - ENSDARG00000052703
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CISD2ENSGALG00000027860Gallus gallus
 CISD2ENSG00000145354Homo sapiens
 Cisd2ENSMUSG00000028165Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
zgc:110843ENSDARG0000007384536
cisd1 / CDGSH iron sulfur domain 1 / Q91WS0* / Q9NZ45* / CDGSH iron-sulfur domain-containing protein 1 *ENSDARG0000007951635


Protein motifs (from Interpro)
Interpro ID Name
 IPR018967  Iron sulphur-containing domain, CDGSH-type
 IPR019610  Iron sulphur domain-containing, mitoNEET, N-terminal


Gene Ontology (GO)
catabolic processcellular component organizationcellular metabolic processprocess utilizing autophagic mechanismanatomical structure developmentagingcatabolic processcellular component organizationcellular metabolic processprocess utilizing autophagic mechanismanatomical structure developmentagingcatabolic processcellular component organizationcellular metabolic processprocess utilizing autophagic mechanismanatomical structure developmentagingcatabolic processcellular component organizationcellular metabolic processprocess utilizing autophagic mechanismanatomical structure developmentagingcatabolic processcellular component organizationcellular metabolic processprocess utilizing autophagic mechanismanatomical structure developmentagingcatabolic processcellular component organizationcellular metabolic processprocess utilizing autophagic mechanismanatomical structure developmentagingcatabolic processcellular component organizationcellular metabolic processprocess utilizing autophagic mechanismanatomical structure developmentagingcatabolic processcellular component organizationcellular metabolic processprocess utilizing autophagic mechanismanatomical structure developmentagingcatabolic processcellular component organizationcellular metabolic processprocess utilizing autophagic mechanismanatomical structure developmentagingcatabolic processcellular component organizationcellular metabolic processprocess utilizing autophagic mechanismanatomical structure developmentagingcatabolic processcatabolic processcellular component orgacellular component organizationcellular metabolic proccellular metabolic processprocess utilizing autopprocess utilizing autophagic mechanismanatomical structure deanatomical structure developmentagingaging
protein bindingion bindingmetal cluster bindingcofactor bindingprotein bindingion bindingmetal cluster bindingcofactor bindingprotein bindingion bindingmetal cluster bindingcofactor bindingprotein bindingion bindingmetal cluster bindingcofactor bindingprotein bindingion bindingmetal cluster bindingcofactor bindingprotein bindingion bindingmetal cluster bindingcofactor bindingprotein bindingion bindingmetal cluster bindingcofactor bindingprotein bindingion bindingmetal cluster bindingcofactor bindingprotein bindingion bindingmetal cluster bindingcofactor bindingprotein bindingion bindingmetal cluster bindingcofactor bindingprotein bindingprotein bindingion bindingion bindingmetal cluster bindingmetal cluster bindingcofactor bindingcofactor binding
cellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellcellorganelleorganellemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0000422 autophagy of mitochondrion ISS
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0010259 multicellular organism aging ISS
 biological_processGO:0010506 regulation of autophagy ISS
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane ISS
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0042803 protein homodimerization activity ISS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051537 2 iron, 2 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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