ENSGALG00000027860


Gallus gallus
membraneCISD2ironautophagyendoplasmicreticulumsulphur-containingdomaincdgsh-typesulphurdomain-containingmitoneetn-terminalmitochondrionmulticellularorganismagingregulationmitochondrialouterintegralcomponentprotein-containingcomplexintracellularmembrane-boundedorganelleproteinhomodimerizationactivitysulfur

Features
Gene ID: ENSGALG00000027860
  
Biological name :CISD2
  
Synonyms : CDGSH iron sulfur domain 2 / CISD2
  
Possible biological names infered from orthology : CDGSH iron-sulfur domain-containing protein 2 / Q8N5K1 / Q9CQB5
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 61334100
Gene end: 61340499
  
Corresponding Affymetrix probe sets: Gga.6242.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000043162
NCBI entrez gene - 422714     See in Manteia.
RefSeq - XM_420668
swissprot - R4GLS1
Ensembl - ENSGALG00000027860
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cisd2ENSDARG00000052703Danio rerio
 CISD2ENSG00000145354Homo sapiens
 Cisd2ENSMUSG00000028165Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CISD1 / CDGSH iron sulfur domain 1 / Q91WS0* / Q9NZ45* / CDGSH iron-sulfur domain-containing protein 1 *ENSGALG0000000270543


Protein motifs (from Interpro)
Interpro ID Name
 IPR018967  Iron sulphur-containing domain, CDGSH-type
 IPR019610  Iron sulphur domain-containing, mitoNEET, N-terminal


Gene Ontology (GO)
catabolic processcellular component organizationcellular metabolic processprocess utilizing autophagic mechanismanatomical structure developmentagingcatabolic processcellular component organizationcellular metabolic processprocess utilizing autophagic mechanismanatomical structure developmentagingcatabolic processcellular component organizationcellular metabolic processprocess utilizing autophagic mechanismanatomical structure developmentagingcatabolic processcellular component organizationcellular metabolic processprocess utilizing autophagic mechanismanatomical structure developmentagingcatabolic processcellular component organizationcellular metabolic processprocess utilizing autophagic mechanismanatomical structure developmentagingcatabolic processcellular component organizationcellular metabolic processprocess utilizing autophagic mechanismanatomical structure developmentagingcatabolic processcellular component organizationcellular metabolic processprocess utilizing autophagic mechanismanatomical structure developmentagingcatabolic processcellular component organizationcellular metabolic processprocess utilizing autophagic mechanismanatomical structure developmentagingcatabolic processcellular component organizationcellular metabolic processprocess utilizing autophagic mechanismanatomical structure developmentagingcatabolic processcellular component organizationcellular metabolic processprocess utilizing autophagic mechanismanatomical structure developmentagingcatabolic processcatabolic processcellular component orgacellular component organizationcellular metabolic proccellular metabolic processprocess utilizing autopprocess utilizing autophagic mechanismanatomical structure deanatomical structure developmentagingaging
protein bindingmetal cluster bindingcofactor bindingprotein bindingmetal cluster bindingcofactor bindingprotein bindingmetal cluster bindingcofactor bindingprotein bindingmetal cluster bindingcofactor bindingprotein bindingmetal cluster bindingcofactor bindingprotein bindingmetal cluster bindingcofactor bindingprotein bindingmetal cluster bindingcofactor bindingprotein bindingmetal cluster bindingcofactor bindingprotein bindingmetal cluster bindingcofactor bindingprotein bindingmetal cluster bindingcofactor bindingprotein bindingprotein bindingmetal cluster bindingmetal cluster bindingcofactor bindingcofactor binding
cellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellcellmembranemembraneorganelleorganelleprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0000422 autophagy of mitochondrion IEA
 biological_processGO:0010259 multicellular organism aging IEA
 biological_processGO:0010506 regulation of autophagy IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0051537 2 iron, 2 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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