ENSDARG00000054374


Danio rerio
domainoligosaccharidealg13tudorotudolichol-linkedbiosyntheticprocessdorsalventralpatternformationtransferasecomplexn-acetylglucosaminyltransferaseactivitybiosynthesisn-glycanprecursordolichollipid-linkedllotransfernascentproteincentralnervouseyenotochord

Features
Gene ID: ENSDARG00000054374
  
Biological name :alg13
  
Synonyms : alg13 / ALG13, UDP-N-acetylglucosaminyltransferase subunit
  
Possible biological names infered from orthology : Q9NP73
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 34233492
Gene end: 34261784
  
Corresponding Affymetrix probe sets: Dr.17317.1.A1_at (Zebrafish Array)   NM_001031838_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000112151
Ensembl peptide - ENSDARP00000136141
Ensembl peptide - ENSDARP00000064319
NCBI entrez gene - 557181     See in Manteia.
RefSeq - NM_001031838
RefSeq - XM_005161414
RefSeq - XM_005161417
RefSeq Peptide - NP_001027008
swissprot - F1QTC9
swissprot - A0A0R4IPL2
swissprot - E9QIU2
ZFIN ID - ZDB-GENE-060307-1
Ensembl - ENSDARG00000054374
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ALG13ENSG00000101901Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
otud4 / OTU deubiquitinase 4 / B2RRE7* / Q01804* / OTU domain-containing protein 4 *ENSDARG0000007781022
otud5b / OTU deubiquitinase 5b / OTUD5* / Q3U2S4* / Q96G74* / OTU deubiquitinase 5* / OTU domain-containing protein 5 *ENSDARG000000568407
Q08BW0 / otud5a / OTU deubiquitinase 5a / OTUD5* / Q3U2S4* / Q96G74* / OTU deubiquitinase 5* / OTU domain-containing protein 5 *ENSDARG000000590067


Protein motifs (from Interpro)
Interpro ID Name
 IPR002999  Tudor domain
 IPR003323  OTU domain


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationanatomical structure developmentnitrogen compound menitrogen compound metabolic processbiosynthetic processbiosynthetic processcellular metabolic pcellular metabolic processprimary metabolic prprimary metabolic processorganic substance meorganic substance metabolic processglycosylationglycosylationanatomical structureanatomical structure development
transferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activity
cellmembraneprotein-containing complexorganellecellmembraneprotein-containing complexorganellecellmembraneprotein-containing complexorganellecellmembraneprotein-containing complexorganellecellmembraneprotein-containing complexorganellecellmembraneprotein-containing complexorganellecellmembraneprotein-containing complexorganellecellmembraneprotein-containing complexorganellecellmembraneprotein-containing complexorganellecellmembraneprotein-containing complexorganellecellcellmembranemembraneprotein-containing complexprotein-containing complexorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0006488 dolichol-linked oligosaccharide biosynthetic process IBA
 biological_processGO:0009953 dorsal/ventral pattern formation IMP
 cellular_componentGO:0043541 UDP-N-acetylglucosamine transferase complex IBA
 molecular_functionGO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity IBA


Pathways (from Reactome)
Pathway description
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000135 notochord notochord malformed , abnormal
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 ZFA:0001094 whole organism whole organism decreased size , abnormal
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 ZFA:0001115 trunk trunk immature , abnormal
trunk decreased thickness , abnormal
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 ZFA:0001117 post-vent region post-vent region curled , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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