ENSDARG00000056805


Danio rerio

Features
Gene ID: ENSDARG00000056805
  
Biological name :plch2b
  
Synonyms : phospholipase C, eta 2b / plch2b
  
Possible biological names infered from orthology : 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 / A2AP18 / O75038 / phospholipase C eta 2 / PLCH2
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 25752198
Gene end: 25777318
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000073784
Ensembl peptide - ENSDARP00000138594
swissprot - A0A0R4IS51
swissprot - F1QS65
ZFIN ID - ZDB-GENE-101112-1
Ensembl - ENSDARG00000056805
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLCH2ENSGALG00000001207Gallus gallus
 PLCH2ENSG00000149527Homo sapiens
 Plch2ENSMUSG00000029055Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
plch2a / phospholipase C, eta 2a / PLCH2* / A2AP18* / O75038* / phospholipase C eta 2* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 *ENSDARG0000005996052
plch1 / phospholipase C, eta 1 / Q4KWH5* / Q4KWH8* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 *ENSDARG0000007925345
plcd4a / phospholipase C, delta 4a / PLCD4* / Q8K3R3* / Q9BRC7* / phospholipase C delta 4*ENSDARG0000005797526
plcl2 / phospholipase C like 2 / Q8K394* / Q9UPR0* / Inactive phospholipase C-like protein 2 *ENSDARG0000009882626
plcd4b / phospholipase C, delta 4b / PLCD4* / Q8K3R3* / Q9BRC7* / phospholipase C delta 4*ENSDARG0000004068425
si:ch211-210g13.5ENSDARG0000006257524
plcd3b / phospholipase C, delta 3b / PLCD3* / Q8N3E9* / Q8K2J0* / phospholipase C delta 3* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 *ENSDARG0000007957224
A5D6R3 / plcd3a / phospholipase C, delta 3a / PLCD3* / Q8N3E9* / Q8K2J0* / phospholipase C delta 3* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 *ENSDARG0000005295723
plcl1 / phospholipase C like 1 / Q15111* / Q3USB7* / phospholipase C like 1 (inactive)* / Inactive phospholipase C-like protein 1 *ENSDARG0000006767623
plcd1b / phospholipase C, delta 1b / PLCD1* / P51178* / phospholipase C delta 1*ENSDARG0000003408021
plcd1a / phospholipase C, delta 1a / PLCD1* / Q8R3B1* / P51178* / phospholipase C delta 1* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 *ENSDARG0000005912321
PLCB4 / phospholipase C beta 4 / Q15147*ENSDARG0000010078621
plcb3 / phospholipase C, beta 3 (phosphatidylinositol-specific) / P51432* / Q01970* / phospholipase C beta 3*ENSDARG0000006824620
PLCB1 / si:ch1073-140o9.2 / Q9NQ66* / Q9Z1B3* / phospholipase C beta 1* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 *ENSDARG0000010972614
PLCB2 / phospholipase C beta 2 / A3KGF7* / Q00722* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 *ENSDARG0000009038113


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000909  Phosphatidylinositol-specific phospholipase C, X domain
 IPR001192  Phosphoinositide phospholipase C family
 IPR001711  Phospholipase C, phosphatidylinositol-specific, Y domain
 IPR001849  Pleckstrin homology domain
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR011993  PH-like domain superfamily
 IPR015359  Phosphoinositide-specific phospholipase C, EF-hand-like domain
 IPR017946  PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
 IPR018247  EF-Hand 1, calcium-binding site
 IPR028393  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0004435 phosphatidylinositol phospholipase C activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of IP3 and IP4 in the cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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