ENSDARG00000059123


Danio rerio

Features
Gene ID: ENSDARG00000059123
  
Biological name :plcd1a
  
Synonyms : phospholipase C, delta 1a / plcd1a
  
Possible biological names infered from orthology : 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 / P51178 / phospholipase C delta 1 / PLCD1 / Q8R3B1
  
Species: Danio rerio
  
Chr. number: 24
Strand: 1
Band:
Gene start: 20372497
Gene end: 20419254
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000113394
Ensembl peptide - ENSDARP00000153856
Ensembl peptide - ENSDARP00000134776
Ensembl peptide - ENSDARP00000117474
Ensembl peptide - ENSDARP00000101132
NCBI entrez gene - 555443     See in Manteia.
RefSeq - NM_001109700
RefSeq Peptide - NP_001103170
swissprot - A0A0R4IGD7
swissprot - E9QFY5
swissprot - F1RBD7
swissprot - E9QD74
ZFIN ID - ZDB-GENE-071004-78
Ensembl - ENSDARG00000059123
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLCD1ENSGALG00000005805Gallus gallus
 PLCD1ENSG00000187091Homo sapiens
 Plcd1ENSMUSG00000010660Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
plcd1b / phospholipase C, delta 1b / PLCD1* / P51178* / phospholipase C delta 1*ENSDARG0000003408062
plcd4a / phospholipase C, delta 4a / PLCD4* / Q8K3R3* / Q9BRC7* / phospholipase C delta 4*ENSDARG0000005797548
plcd4b / phospholipase C, delta 4b / PLCD4* / Q8K3R3* / Q9BRC7* / phospholipase C delta 4*ENSDARG0000004068446
A5D6R3 / plcd3a / phospholipase C, delta 3a / PLCD3* / Q8N3E9* / Q8K2J0* / phospholipase C delta 3* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 *ENSDARG0000005295745
plcd3b / phospholipase C, delta 3b / PLCD3* / Q8N3E9* / Q8K2J0* / phospholipase C delta 3* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 *ENSDARG0000007957244
plch2a / phospholipase C, eta 2a / PLCH2* / A2AP18* / O75038* / phospholipase C eta 2* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 *ENSDARG0000005996036
plcl2 / phospholipase C like 2 / Q8K394* / Q9UPR0* / Inactive phospholipase C-like protein 2 *ENSDARG0000009882635
plch1 / phospholipase C, eta 1 / Q4KWH5* / Q4KWH8* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 *ENSDARG0000007925334
si:ch211-210g13.5ENSDARG0000006257533
plcl1 / phospholipase C like 1 / Q15111* / Q3USB7* / phospholipase C like 1 (inactive)* / Inactive phospholipase C-like protein 1 *ENSDARG0000006767629
plcb3 / phospholipase C, beta 3 (phosphatidylinositol-specific) / P51432* / Q01970* / phospholipase C beta 3*ENSDARG0000006824629
PLCB4 / phospholipase C beta 4 / Q15147*ENSDARG0000010078629
plch2b / phospholipase C, eta 2b / PLCH2* / A2AP18* / O75038* / phospholipase C eta 2* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 *ENSDARG0000005680528
PLCB1 / si:ch1073-140o9.2 / Q9NQ66* / Q9Z1B3* / phospholipase C beta 1* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 *ENSDARG0000010972619
PLCB2 / phospholipase C beta 2 / A3KGF7* / Q00722* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 *ENSDARG0000009038116


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000909  Phosphatidylinositol-specific phospholipase C, X domain
 IPR001192  Phosphoinositide phospholipase C family
 IPR001711  Phospholipase C, phosphatidylinositol-specific, Y domain
 IPR001849  Pleckstrin homology domain
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR011993  PH-like domain superfamily
 IPR015359  Phosphoinositide-specific phospholipase C, EF-hand-like domain
 IPR017946  PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0004435 phosphatidylinositol phospholipase C activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of IP3 and IP4 in the cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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