ENSGALG00000005805


Gallus gallus

Features
Gene ID: ENSGALG00000005805
  
Biological name :PLCD1
  
Synonyms : phospholipase C delta 1 / PLCD1
  
Possible biological names infered from orthology : 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 / P51178 / Q8R3B1
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 4635397
Gene end: 4683167
  
Corresponding Affymetrix probe sets: Gga.12980.1.S1_s_at (Chicken Array)   Gga.17294.1.S1_at (Chicken Array)   Gga.3447.1.S1_at (Chicken Array)   GgaAffx.26610.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000009307
NCBI entrez gene - 420416     See in Manteia.
RefSeq - XM_004939119
RefSeq - XM_418522
RefSeq - XM_015281118
RefSeq - XM_015281119
swissprot - E1C3D8
Ensembl - ENSGALG00000005805
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plcd1aENSDARG00000059123Danio rerio
 plcd1bENSDARG00000034080Danio rerio
 PLCD1ENSG00000187091Homo sapiens
 Plcd1ENSMUSG00000010660Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PLCD4 / phospholipase C delta 4 / Q8K3R3* / Q9BRC7*ENSGALG0000002668749
PLCD3 / phospholipase C delta 3 / Q8K2J0* / Q8N3E9* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 *ENSGALG0000004521245
PLCH2 / phospholipase C eta 2 / A2AP18* / O75038* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 *ENSGALG0000000120739
PLCL2 / phospholipase C like 2 / Q8K394* / Q9UPR0* / Inactive phospholipase C-like protein 2 *ENSGALG0000001124838
PLCH1 / phospholipase C eta 1 / Q4KWH5* / Q4KWH8* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 *ENSGALG0000001031237
PLCL1 / phospholipase C like 1 (inactive) / Q15111* / Q3USB7* / Inactive phospholipase C-like protein 1 *ENSGALG0000000811336
ENSGALG0000000334535
PLCZ1 / Q2VRL0 / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 / Q86YW0* / Q8K4D7* / phospholipase C zeta 1*ENSGALG0000001312334
PLCB1 / phospholipase C beta 1 / Q9NQ66* / Q9Z1B3* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 *ENSGALG0000000887532
PLCB4 / phospholipase C beta 4 / Q15147*ENSGALG0000000890732
PLCB2 / phospholipase C beta 2 / A3KGF7* / Q00722* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 *ENSGALG0000004210532


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000909  Phosphatidylinositol-specific phospholipase C, X domain
 IPR001192  Phosphoinositide phospholipase C family
 IPR001711  Phospholipase C, phosphatidylinositol-specific, Y domain
 IPR001849  Pleckstrin homology domain
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR011993  PH-like domain superfamily
 IPR015359  Phosphoinositide-specific phospholipase C, EF-hand-like domain
 IPR017946  PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
 IPR018247  EF-Hand 1, calcium-binding site
 IPR028391  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0060716 labyrinthine layer blood vessel development IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0001786 phosphatidylserine binding IEA
 molecular_functionGO:0004435 phosphatidylinositol phospholipase C activity IEA
 molecular_functionGO:0004629 phospholipase C activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0032794 GTPase activating protein binding IEA
 molecular_functionGO:0070300 phosphatidic acid binding IEA
 molecular_functionGO:1901981 phosphatidylinositol phosphate binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of IP3 and IP4 in the cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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