ENSGALG00000010312


Gallus gallus

Features
Gene ID: ENSGALG00000010312
  
Biological name :PLCH1
  
Synonyms : phospholipase C eta 1 / PLCH1
  
Possible biological names infered from orthology : 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 / Q4KWH5 / Q4KWH8
  
Species: Gallus gallus
  
Chr. number: 9
Strand: 1
Band:
Gene start: 23080040
Gene end: 23133003
  
Corresponding Affymetrix probe sets: Gga.17381.1.S1_at (Chicken Array)   Gga.2646.1.S1_at (Chicken Array)   Gga.2646.1.S1_s_at (Chicken Array)   GgaAffx.20398.1.S1_s_at (Chicken Array)   GgaAffx.23197.1.S1_s_at (Chicken Array)   GgaAffx.6501.2.S1_at (Chicken Array)   GgaAffx.6501.5.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000016765
NCBI entrez gene - 425030     See in Manteia.
RefSeq - XM_015291816
RefSeq - XM_015291817
RefSeq - XM_015291818
RefSeq - XM_015291819
RefSeq - XM_015291820
RefSeq - XM_015291821
RefSeq - XM_015291822
RefSeq - XM_015291823
RefSeq - XM_422832
RefSeq - XM_004943562
swissprot - E1C7E3
Ensembl - ENSGALG00000010312
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plch1ENSDARG00000079253Danio rerio
 PLCH1ENSG00000114805Homo sapiens
 Plch1ENSMUSG00000036834Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PLCH2 / phospholipase C eta 2 / A2AP18* / O75038* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 *ENSGALG0000000120735
PLCL2 / phospholipase C like 2 / Q8K394* / Q9UPR0* / Inactive phospholipase C-like protein 2 *ENSGALG0000001124820
PLCL1 / phospholipase C like 1 (inactive) / Q15111* / Q3USB7* / Inactive phospholipase C-like protein 1 *ENSGALG0000000811319
PLCD4 / phospholipase C delta 4 / Q8K3R3* / Q9BRC7*ENSGALG0000002668719
ENSGALG0000000334517
PLCD1 / phospholipase C delta 1 / P51178* / Q8R3B1* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 *ENSGALG0000000580517
PLCB2 / phospholipase C beta 2 / A3KGF7* / Q00722* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 *ENSGALG0000004210516
PLCD3 / phospholipase C delta 3 / Q8K2J0* / Q8N3E9* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 *ENSGALG0000004521216
PLCB1 / phospholipase C beta 1 / Q9NQ66* / Q9Z1B3* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 *ENSGALG0000000887515
PLCB4 / phospholipase C beta 4 / Q15147*ENSGALG0000000890715
PLCZ1 / Q2VRL0 / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 / Q86YW0* / Q8K4D7* / phospholipase C zeta 1*ENSGALG0000001312314


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000909  Phosphatidylinositol-specific phospholipase C, X domain
 IPR001192  Phosphoinositide phospholipase C family
 IPR001711  Phospholipase C, phosphatidylinositol-specific, Y domain
 IPR001849  Pleckstrin homology domain
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR011993  PH-like domain superfamily
 IPR015359  Phosphoinositide-specific phospholipase C, EF-hand-like domain
 IPR017946  PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
 IPR018247  EF-Hand 1, calcium-binding site
 IPR028392  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0048015 phosphatidylinositol-mediated signaling IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004435 phosphatidylinositol phospholipase C activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0050429 calcium-dependent phospholipase C activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of IP3 and IP4 in the cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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