ENSGALG00000013123


Gallus gallus

Features
Gene ID: ENSGALG00000013123
  
Biological name :PLCZ1
  
Synonyms : 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 / PLCZ1 / Q2VRL0
  
Possible biological names infered from orthology : phospholipase C zeta 1 / Q86YW0 / Q8K4D7
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 64235354
Gene end: 64278321
  
Corresponding Affymetrix probe sets: Gga.15575.1.S1_at (Chicken Array)   GgaAffx.24114.1.S1_s_at (Chicken Array)   GgaAffx.8337.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000021386
NCBI entrez gene - 418182     See in Manteia.
RefSeq - NM_001039273
RefSeq Peptide - NP_001034362
swissprot - Q2VRL0
Ensembl - ENSGALG00000013123
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLCZ1ENSG00000139151Homo sapiens
 Plcz1ENSMUSG00000030230Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PLCD4 / phospholipase C delta 4 / Q8K3R3* / Q9BRC7*ENSGALG0000002668743
PLCD1 / phospholipase C delta 1 / P51178* / Q8R3B1* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 *ENSGALG0000000580541
PLCH2 / phospholipase C eta 2 / A2AP18* / O75038* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 *ENSGALG0000000120738
PLCL2 / phospholipase C like 2 / Q8K394* / Q9UPR0* / Inactive phospholipase C-like protein 2 *ENSGALG0000001124838
PLCD3 / phospholipase C delta 3 / Q8K2J0* / Q8N3E9* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 *ENSGALG0000004521238
PLCH1 / phospholipase C eta 1 / Q4KWH5* / Q4KWH8* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 *ENSGALG0000001031237
ENSGALG0000000334535
PLCL1 / phospholipase C like 1 (inactive) / Q15111* / Q3USB7* / Inactive phospholipase C-like protein 1 *ENSGALG0000000811335
PLCB2 / phospholipase C beta 2 / A3KGF7* / Q00722* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 *ENSGALG0000004210532
PLCB1 / phospholipase C beta 1 / Q9NQ66* / Q9Z1B3* / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 *ENSGALG0000000887531
PLCB4 / phospholipase C beta 4 / Q15147*ENSGALG0000000890731


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000909  Phosphatidylinositol-specific phospholipase C, X domain
 IPR001192  Phosphoinositide phospholipase C family
 IPR001711  Phospholipase C, phosphatidylinositol-specific, Y domain
 IPR011992  EF-hand domain pair
 IPR015359  Phosphoinositide-specific phospholipase C, EF-hand-like domain
 IPR017946  PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
 IPR028395  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007338 single fertilization IEA
 biological_processGO:0007343 egg activation IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0060470 positive regulation of cytosolic calcium ion concentration involved in egg activation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0045120 pronucleus IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0061827 sperm head IEA
 molecular_functionGO:0004435 phosphatidylinositol phospholipase C activity IEA
 molecular_functionGO:0004629 phospholipase C activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0010314 phosphatidylinositol-5-phosphate binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0032266 phosphatidylinositol-3-phosphate binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of IP3 and IP4 in the cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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