ENSDARG00000057429


Danio rerio
activityarg1ureohydrolasearginaseureacyclehydrolasemanganese-bindingsiteargininemetabolicprocessactingcarbon-nitrogenpeptidebondslinearamidinesmetalionbindingneutrophildegranulation

Features
Gene ID: ENSDARG00000057429
  
Biological name :arg1
  
Synonyms : arg1 / arginase 1
  
Possible biological names infered from orthology : P05089 / Q61176
  
Species: Danio rerio
  
Chr. number: 12
Strand: -1
Band:
Gene start: 9597151
Gene end: 9617770
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000097045
NCBI entrez gene - 570368     See in Manteia.
RefSeq - NM_001045197
RefSeq Peptide - NP_001038662
swissprot - E7F8R4
ZFIN ID - ZDB-GENE-040724-181
Ensembl - ENSDARG00000057429
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARG1ENSG00000118520Homo sapiens
 Arg1ENSMUSG00000019987Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
arg2 / arginase 2 / O08691* / P78540* / Arginase-2, mitochondrial *ENSDARG0000003926953
agmat / agmatine ureohydrolase (agmatinase) / Q9BSE5* / agmatinase*ENSDARG0000005970021


Protein motifs (from Interpro)
Interpro ID Name
 IPR006035  Ureohydrolase
 IPR014033  Arginase
 IPR020855  Ureohydrolase, manganese-binding site


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processsmall molecule metabolic processorganic substance metabolic processprimary metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processsmall molecule metabolic processorganic substance metabolic processprimary metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processsmall molecule metabolic processorganic substance metabolic processprimary metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processsmall molecule metabolic processorganic substance metabolic processprimary metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processsmall molecule metabolic processorganic substance metabolic processprimary metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processsmall molecule metabolic processorganic substance metabolic processprimary metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processsmall molecule metabolic processorganic substance metabolic processprimary metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processsmall molecule metabolic processorganic substance metabolic processprimary metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processsmall molecule metabolic processorganic substance metabolic processprimary metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processsmall molecule metabolic processorganic substance metabolic processprimary metabolic processnitrogen compound metabnitrogen compound metabolic processbiosynthetic processbiosynthetic processcellular metabolic proccellular metabolic processsmall molecule metabolismall molecule metabolic processorganic substance metaborganic substance metabolic processprimary metabolic proceprimary metabolic process
hydrolase activityion bindinghydrolase activityion bindinghydrolase activityion bindinghydrolase activityion bindinghydrolase activityion bindinghydrolase activityion bindinghydrolase activityion bindinghydrolase activityion bindinghydrolase activityion bindinghydrolase activityion bindinghydrolase activityhydrolase activityion bindingion binding
TypeGO IDTermEv.Code
 biological_processGO:0000050 urea cycle IEA
 biological_processGO:0006525 arginine metabolic process IEA
 molecular_functionGO:0004053 arginase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Urea cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000057429 arg1 / arginase 1 / P05089* / Q61176*  / complex






 

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