ENSDARG00000057633
Danio rerio receptor cell cxcr4a chemokine migration involved signaling development somite activity g rhodopsin-like morphogenesis sprouting angiogenesis signal g-protein coupled pathway neural crest membrane receptors pancreas artery protein-coupled family cxc atypical gpcr tm
Features Gene ID: ENSDARG00000057633 Biological name :cxcr4a Synonyms : chemokine (C-X-C motif) receptor 4a / cxcr4a Possible biological names infered from orthology : C-X-C motif chemokine receptor 4 / CXCR4 / Mus musculus chemokine (C-X-C motif) receptor 4 (Cxcr4), transcript variant 2, mRNA. / P61073 Species: Danio rerio Chr. number: 6 Strand: 1 Band: Gene start: 12922002 Gene end: 12923727 Corresponding Affymetrix probe sets: Dr.15055.1.S1_at (Zebrafish Array) NM_131882_at (Zebrafish Genome Array with custom cdf files) Cross references: Ensembl peptide - ENSDARP00000123851 Ensembl peptide - ENSDARP00000074800 NCBI entrez gene - 140747
See in Manteia .
RefSeq - NM_131882 RefSeq Peptide - NP_571957 swissprot - F8W4X7 swissprot - F1QCB2 ZFIN ID - ZDB-GENE-020102-1 Ensembl - ENSDARG00000057633
See expression report in BioGPS See gene description in Wikigenes See co-cited genes in PubMed Ortholog prediction (from Ensembl )
Paralog prediction (from Ensembl ) cxcr4b / chemokine (C-X-C motif), receptor 4b / CXCR4* / P61073* / C-X-C motif chemokine receptor 4* / Mus musculus chemokine (C-X-C motif) receptor 4 (Cxcr4), transcript variant 2, mRNA.* ENSDARG00000041959 73 cxcr3.1 / chemokine (C-X-C motif) receptor 3, tandem duplicate 1 / CXCR3* / O88410* / P49682* / C-X-C motif chemokine receptor 3* / C-X-C chemokine receptor type 3 * ENSDARG00000007358 32 E9QJ73 / cxcr3.2 / chemokine (C-X-C motif) receptor 3, tandem duplicate 2 ENSDARG00000041041 32 cxcr5 / chemokine (C-X-C motif) receptor 5 / P32302* / C-X-C motif chemokine receptor 5* ENSDARG00000010514 31 cabz01093075.1 / CCR8* / P51685* / C-C motif chemokine receptor 8* ENSDARG00000086616 31 ccr6a / chemokine (C-C motif) receptor 6a / CCR6* / P51684* / O54689* / C-C motif chemokine receptor 6* / Mus musculus chemokine (C-C motif) receptor 6 (Ccr6), transcript variant 7, mRNA.* ENSDARG00000087474 31 ccr9b / chemokine (C-C motif) receptor 9b / CCR9* / Q9WUT7* / P51686* / C-C chemokine receptor type 9 * / C-C motif chemokine receptor 9* ENSDARG00000099738 31 cxcr2 / chemokine (C-X-C motif) receptor 2 / CXCR1* / P25024* / P25025* / P35343* / Q810W6* / C-X-C chemokine receptor type 1 * / C-X-C motif chemokine receptor 2* / C-X-C chemokine recepto... ENSDARG00000054975 30 ccr9a / chemokine (C-C motif) receptor 9a / CCR9* / Q9WUT7* / P51686* / C-C chemokine receptor type 9 * / C-C motif chemokine receptor 9* ENSDARG00000055186 30 ackr4a / atypical chemokine receptor 4a / ACKR4* / Q924I3* / Q9NPB9* / atypical chemokine receptor 4* ENSDARG00000078729 30 ccr8.1 / chemokine (C-C motif) receptor 8.1 / CCR8* / P56484* / P51685* / C-C chemokine receptor type 8 * / C-C motif chemokine receptor 8* ENSDARG00000095789 30 ackr4b / atypical chemokine receptor 4b / ACKR4* / Q924I3* / Q9NPB9* / atypical chemokine receptor 4* ENSDARG00000040133 29 ccr7 / chemokine (C-C motif) receptor 7 / P32248* / P47774* / C-C chemokine receptor type 7 * / C-C motif chemokine receptor 7* ENSDARG00000044561 29 ccr2 / si:ch211-207g17.3 / CCR5* / CCR1* / CCR3* / CCR4* / P51675* / P51676* / P51677* / P51678* / P51679* / P51682* / P51681* / P51683* / P51680* / Ccr1l1* / P32246* / P41597* / C-C motif ... ENSDARG00000105363 29 ccr6b / chemokine (C-C motif) receptor 6b / CCR6* / P51684* / O54689* / C-C motif chemokine receptor 6* / Mus musculus chemokine (C-C motif) receptor 6 (Ccr6), transcript variant 7, mRNA.* ENSDARG00000038968 28 si:ch73-54b5.2 ENSDARG00000052088 28 ccr2 / chemokine (C-C motif) receptor 2 / CCR3* / CCR5* / CCR1* / CCR4* / P51681* / P41597* / P51675* / P51676* / P51677* / P51678* / P51679* / P51680* / P51682* / P51683* / Ccr1l1* / P3224... ENSDARG00000079829 28 ccr12a / chemokine (C-C motif) receptor 12a ENSDARG00000038541 27 ccr12b.1 / chemokine (C-C motif) receptor 12b, tandem duplicate 1 ENSDARG00000059410 26 ccr11.1 / chemokine (C-C motif) receptor 11.1 / CCR3* / CCR2* / CCR4* / CCR5* / CCR1* / P51681* / P51683* / P41597* / P51675* / P51676* / P51677* / P51678* / P51679* / P51680* / P51682* / C... ENSDARG00000070755 26
Protein motifs (from Interpro ) IPR000276 G protein-coupled receptor, rhodopsin-like IPR000355 Chemokine receptor family IPR001277 CXC chemokine receptor 4/atypical chemokine receptor 2 IPR017452 GPCR, rhodopsin-like, 7TM
Gene Ontology (GO ) cellular component organization anatomical structure development cellular developmental process localization of cell movement of cell or subcellular component tissue migration response to external stimulus response to chemical cell communication cellular response to stimulus cellular component biogenesis actin filament-based process cellular component organization anatomical structure development cellular developmental process localization of cell movement of cell or subcellular component tissue migration response to external stimulus response to chemical cell communication cellular response to stimulus cellular component biogenesis actin filament-based process cellular component organization anatomical structure development cellular developmental process localization of cell movement of cell or subcellular component tissue migration response to external stimulus response to chemical cell communication cellular response to stimulus cellular component biogenesis actin filament-based process cellular component organization anatomical structure development cellular developmental process localization of cell movement of cell or subcellular component tissue migration response to external stimulus response to chemical cell communication cellular response to stimulus cellular component biogenesis actin filament-based process cellular component organization anatomical structure development cellular developmental process localization of cell movement of cell or subcellular component tissue migration response to external stimulus response to chemical cell communication cellular response to stimulus cellular component biogenesis actin filament-based process cellular component organization anatomical structure development cellular developmental process localization of cell movement of cell or subcellular component tissue migration response to external stimulus response to chemical cell communication cellular response to stimulus cellular component biogenesis actin filament-based process cellular component organization anatomical structure development cellular developmental process localization of cell movement of cell or subcellular component tissue migration response to external stimulus response to chemical cell communication cellular response to stimulus cellular component biogenesis actin filament-based process cellular component organization anatomical structure development cellular developmental process localization of cell movement of cell or subcellular component tissue migration response to external stimulus response to chemical cell communication cellular response to stimulus cellular component biogenesis actin filament-based process cellular component organization anatomical structure development cellular developmental process localization of cell movement of cell or subcellular component tissue migration response to external stimulus response to chemical cell communication cellular response to stimulus cellular component biogenesis actin filament-based process cellular component organization anatomical structure development cellular developmental process localization of cell movement of cell or subcellular component tissue migration response to external stimulus response to chemical cell communication cellular response to stimulus cellular component biogenesis actin filament-based process cellular cocellular component organization anatomical anatomical structure development cellular decellular developmental process localizatiolocalization of cell movement ofmovement of cell or subcellular component tissue migrtissue migration response toresponse to external stimulus response toresponse to chemical cell communcell communication cellular recellular response to stimulus cellular cocellular component biogenesis actin filamactin filament-based process signaling receptor activity signaling receptor activity signaling receptor activity signaling receptor activity signaling receptor activity signaling receptor activity signaling receptor activity signaling receptor activity signaling receptor activity signaling receptor activity signaling receptor activitysignaling receptor activity membrane membrane membrane membrane membrane membrane membrane membrane membrane membrane membranemembrane
Pathways (from Reactome )
Phenotype (from MGI , Zfin or HPO ) ZFA:0000017 endoderm endoderm mislocalised anteriorly , abnormal
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ZFA:0000037 anatomical structure anatomical structure increased amount , abnormal
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ZFA:0000112 gut gut morphology , abnormal gut bifurcated , abnormal
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ZFA:0000123 liver liver decreased size , abnormal liver duplicated , abnormal
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ZFA:0000140 pancreas pancreas morphology , abnormal pancreas decreased size , abnormal pancreas pancreatic B cell dispersed , abnormal pancreas duplicated , abnormal
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ZFA:0000155 somite somite morphology , abnormal somite cellular quality , abnormal somite increased amount , abnormal somite increased distribution , abnormal
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ZFA:0001052 primordial hindbrain channel primordial hindbrain channel angiogenic sprout mislocalised , abnormal primordial hindbrain channel angiogenic sprout decreased amount , abnormal
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ZFA:0001054 lateral dorsal aorta lateral dorsal aorta malformed , abnormal
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ZFA:0001194 cranial neural crest cranial neural crest filopodium decreased length , abnormal
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ZFA:0001260 endocrine pancreas endocrine pancreas mislocalised , abnormal endocrine pancreas malformed , abnormal
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ZFA:0001269 regenerating fin regenerating fin blood vessel endothelial cell migration disrupted , abnormal regenerating fin caudal fin lacks parts or has fewer parts of type artery , abnormal regenerating fin caudal fin vasculature decreased length , abnormal regenerating fin caudal fin vasculature decreased area , abnormal
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ZFA:0001338 intestine intestine duplicated , abnormal
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ZFA:0001462 somite border somite border morphology , abnormal somite border malformed , abnormal somite border centrosome spatial pattern , abnormal somite border mesenchymal to epithelial transition decreased occurrence , abnormal somite border epithelial cell morphology , abnormal
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ZFA:0005002 basilar artery basilar artery unlumenized , abnormal basilar artery agenesis , abnormal basilar artery absent , abnormal
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ZFA:0005020 central artery central artery malformed , abnormal central artery physical object quality , abnormal
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ZFA:0005110 thoracic duct thoracic duct lymphangiogenesis decreased process quality , abnormal
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ZFA:0009036 blood vessel endothelial cell blood vessel endothelial cell mislocalised , abnormal
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ZFA:0009139 endodermal cell endodermal cell circular , abnormal endodermal cell filopodium orientation whole organism dorsal-ventral axis, abnormal endodermal cell filopodium decreased amount , abnormal endodermal cell mislocalised anteriorly , abnormal endodermal cell displaced to margin , abnormal
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Interacting proteins (from Reactome )No match
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