ENSDARG00000058815


Danio rerio

Features
Gene ID: ENSDARG00000058815
  
Biological name :ihhb
  
Synonyms : ihhb / Indian hedgehog homolog b
  
Possible biological names infered from orthology : IHH / indian hedgehog / P97812 / Q14623
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 7059999
Gene end: 7082108
  
Corresponding Affymetrix probe sets: Dr.114.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000076199
Ensembl peptide - ENSDARP00000108406
NCBI entrez gene - 30299     See in Manteia.
swissprot - F1QTR5
swissprot - F1R9L0
ZFIN ID - ZDB-GENE-980526-135
Ensembl - ENSDARG00000058815
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IHHENSGALG00000011347Gallus gallus
 IHHENSG00000163501Homo sapiens
 IhhENSMUSG00000006538Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ihha / Indian hedgehog homolog a / IHH* / Q14623* / P97812* / indian hedgehog*ENSDARG0000005873366
shha / Q92008 / sonic hedgehog aENSDARG0000006856758
shhb / Q90419 / sonic hedgehog bENSDARG0000003886756
dhh / desert hedgehog / O43323* / Q61488* / Desert hedgehog protein Desert hedgehog protein N-product Desert hedgehog protein C-product*ENSDARG0000003706244


Protein motifs (from Interpro)
Interpro ID Name
 IPR000320  Hedgehog, N-terminal signalling domain
 IPR001657  Hedgehog protein
 IPR001767  Hedgehog protein, Hint domain
 IPR003586  Hint domain C-terminal
 IPR003587  Hint domain N-terminal
 IPR006141  Intein N-terminal splicing region
 IPR009045  Hedgehog signalling/DD-peptidase zinc-binding domain superfamily
 IPR028992  Hedgehog/Intein (Hint) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007267 cell-cell signaling IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016539 intein-mediated protein splicing IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Hedgehog ligand biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000075 spinal cord spinal cord spinal cord oligodendrocyte cell fate specification disrupted , abnormal
spinal cord oligodendrocyte decreased amount , abnormal
spinal cord glioblast (sensu Vertebrata) decreased amount , abnormal
spinal cord neuron increased amount , abnormal
spinal cord regulation of oligodendrocyte progenitor proliferation disrupted , abnormal
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 ZFA:0009169 glioblast (sensu Vertebrata) glioblast (sensu Vertebrata) cell division increased occurrence , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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