ENSDARG00000059858


Danio rerio

Features
Gene ID: ENSDARG00000059858
  
Biological name :pappab
  
Synonyms : pappab / pregnancy-associated plasma protein A, pappalysin 1b
  
Possible biological names infered from orthology : PAPPA / pappalysin 1 / Q13219 / Q8R4K8
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 63913310
Gene end: 64104012
  
Corresponding Affymetrix probe sets: Dr.14210.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000078119
Ensembl peptide - ENSDARP00000118115
Ensembl peptide - ENSDARP00000123152
NCBI entrez gene - 101448001     See in Manteia.
RefSeq - NM_001278808
RefSeq Peptide - NP_001265737
swissprot - F1Q5Q4
swissprot - B0R0F2
swissprot - F1QEV4
ZFIN ID - ZDB-GENE-060526-71
Ensembl - ENSDARG00000059858
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PAPPAENSGALG00000007079Gallus gallus
 PAPPAENSG00000182752Homo sapiens
 PappaENSMUSG00000028370Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pappaa / pregnancy-associated plasma protein A, pappalysin 1a / PAPPA* / Q8R4K8* / Q13219* / pappalysin 1*ENSDARG0000010109073
pappa2 / pappalysin 2 / Q9BXP8*ENSDARG0000007602042


Protein motifs (from Interpro)
Interpro ID Name
 IPR000436  Sushi/SCR/CCP domain
 IPR000800  Notch domain
 IPR006558  LamG-like jellyroll fold
 IPR008754  Peptidase M43, pregnancy-associated plasma-A
 IPR011936  Myxococcus cysteine-rich repeat
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR030433  Pappalysin-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0043009 chordate embryonic development IMP
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IDA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism decreased length , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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