ENSDARG00000061214


Danio rerio
lipinlpin2lnsprocesstriglyceridetranscriptionactivitysynthesisn-terminalnedsmpsuperfamilypitpmiddledomainfattyacidcatabolicdephosphorylationbiosyntheticregulationrnapolymeraseiinucleusendoplasmicreticulummembranecytosolcoactivatorphosphatidate

Features
Gene ID: ENSDARG00000061214
  
Biological name :lpin2
  
Synonyms : lipin 2 / lpin2
  
Possible biological names infered from orthology : Mus musculus lipin 2 (Lpin2), transcript variant 3, mRNA. / Q92539 / Q99PI5
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 30960351
Gene end: 30984508
  
Corresponding Affymetrix probe sets: Dr.6402.1.A1_at (Zebrafish Array)   XM_702758_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000114217
Ensembl peptide - ENSDARP00000079677
NCBI entrez gene - 558422     See in Manteia.
RefSeq - XM_005163454
RefSeq - XM_702758
swissprot - F1RAK9
swissprot - F1QXM6
ZFIN ID - ZDB-GENE-060503-153
Ensembl - ENSDARG00000061214
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LPIN2ENSGALG00000014836Gallus gallus
 LPIN2ENSG00000101577Homo sapiens
 Lpin2ENSMUSG00000024052Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
lpin1 / lipin 1 / Q14693* / Mus musculus lipin 1 (Lpin1), transcript variant 4, mRNA.*ENSDARG0000002023950
si:ch73-21k16.1 / LPIN1* / Q14693* / lipin 1* / Mus musculus lipin 1 (Lpin1), transcript variant 4, mRNA.*ENSDARG0000010338047
zgc:123305 / LPIN3* / Q99PI4* / Q9BQK8* / lipin 3* / Phosphatidate phosphatase LPIN3 *ENSDARG0000001556345


Protein motifs (from Interpro)
Interpro ID Name
 IPR007651  Lipin, N-terminal
 IPR013209  Lipin/Ned1/Smp2 (LNS2)
 IPR023214  HAD superfamily
 IPR031315  LNS2/PITP
 IPR031703  Lipin, middle domain


Gene Ontology (GO)
catabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processbiosynthetic processnitrogen compound metabolic processcatabolic processcatabolic processcellular metabolic pcellular metabolic processprimary metabolic prprimary metabolic processsmall molecule metabsmall molecule metabolic processorganic substance meorganic substance metabolic processbiosynthetic processbiosynthetic processnitrogen compound menitrogen compound metabolic process
transcription coregulator activityhydrolase activitytranscription coregulator activityhydrolase activitytranscription coregulator activityhydrolase activitytranscription coregulator activityhydrolase activitytranscription coregulator activityhydrolase activitytranscription coregulator activityhydrolase activitytranscription coregulator activityhydrolase activitytranscription coregulator activityhydrolase activitytranscription coregulator activityhydrolase activitytranscription coregulator activityhydrolase activitytranscription coregulator activitytranscription coregulator activityhydrolase activityhydrolase activity
cellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellcellorganelleorganellemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0009062 fatty acid catabolic process IBA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0019432 triglyceride biosynthetic process IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IBA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0003713 transcription coactivator activity IBA
 molecular_functionGO:0008195 phosphatidate phosphatase activity IBA


Pathways (from Reactome)
Pathway description
Synthesis of PC
Synthesis of PE
Depolymerisation of the Nuclear Lamina
Triglyceride biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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