ENSDARG00000061338


Danio rerio

Features
Gene ID: ENSDARG00000061338
  
Biological name :ddx6
  
Synonyms : ddx6 / DEAD (Asp-Glu-Ala-Asp) box helicase 6
  
Possible biological names infered from orthology : DEAD-box helicase 6 / Mus musculus DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 (Ddx6), transcript variant 4, mRNA. / P26196 / P54823
  
Species: Danio rerio
  
Chr. number: 18
Strand: -1
Band:
Gene start: 43865901
Gene end: 43884044
  
Corresponding Affymetrix probe sets: Dr.24222.1.A1_at (Zebrafish Array)   Dr.3865.1.A1_at (Zebrafish Array)   XM_679831_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000081816
Ensembl peptide - ENSDARP00000149027
NCBI entrez gene - 564633     See in Manteia.
RefSeq - XM_679831
swissprot - E7FD91
ZFIN ID - ZDB-GENE-070912-83
Ensembl - ENSDARG00000061338
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DDX6ENSGALG00000033064Gallus gallus
 DDX6ENSG00000110367Homo sapiens
 Ddx6ENSMUSG00000032097Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ddx61 / DEAD (Asp-Glu-Ala-Asp) box helicase 61ENSDARG0000001842578


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006417 regulation of translation IBA
 biological_processGO:0009408 response to heat IGI
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 biological_processGO:0033962 cytoplasmic mRNA processing body assembly IBA
 biological_processGO:0034063 stress granule assembly IMP
 cellular_componentGO:0000932 P-body IBA
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0010494 cytoplasmic stress granule IBA
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
mRNA decay by 5 to 3 exoribonuclease


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000135 notochord notochord morphology , abnormal
Show

 ZFA:0000155 somite somite morphology , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased life span , abnormal
Show

 ZFA:0001115 trunk trunk cytoplasmic stress granule absent , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved , abnormal
Show

 ZFA:0005024 trunk vasculature trunk vasculature morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr