ENSDARG00000061459


Danio rerio
domainexchangesi:dkey-253i9.4factoractivitygtpasecyclicguaninenucleotiderassignaltransductionregulationguanyl-nucleotideras-associatingranucleotide-bindingras-liken-terminalpdzguanine-nucleotidefactorscatalyticrmlc-likejellyrollfoldnucleotide-binding-likesuperfamilysmallmediated

Features
Gene ID: ENSDARG00000061459
  
Biological name :si:dkey-253i9.4
  
Synonyms : si:dkey-253i9.4
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 21135012
Gene end: 21204114
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000120972
Ensembl peptide - ENSDARP00000148095
Ensembl peptide - ENSDARP00000082104
Ensembl peptide - ENSDARP00000118432
swissprot - E9QI83
swissprot - E9QJ00
swissprot - F1QPF1
ZFIN ID - ZDB-GENE-090313-280
Ensembl - ENSDARG00000061459
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rapgef2 / Rap guanine nucleotide exchange factor (GEF) 2 / Q8CHG7* / Q9Y4G8* / Rap guanine nucleotide exchange factor 2*ENSDARG0000000548270
rapgef6 / Rap guanine nucleotide exchange factor (GEF) 6 / Q8TEU7* / AC008695.1* / Rap guanine nucleotide exchange factor 6*ENSDARG0000001094546
zgc:171558 / Q8WZA2* / Q9EQZ6* / RAPGEF4* / Rap guanine nucleotide exchange factor 4* / Rap guanine nucleotide exchange factor (GEF) 4*ENSDARG0000007592417
rapgef4 / Rap guanine nucleotide exchange factor (GEF) 4 / Q8WZA2* / Q9EQZ6* / Rap guanine nucleotide exchange factor 4*ENSDARG0000007987217
rapgef3 / Rap guanine nucleotide exchange factor (GEF) 3 / Q8VCC8* / O95398* / Rap guanine nucleotide exchange factor 3* / Mus musculus Rap guanine nucleotide exchange factor (GEF) 3 (Rapge...ENSDARG0000007929114
rapgef5a / Rap guanine nucleotide exchange factor (GEF) 5a / Q92565* / RAPGEF5* / Rap guanine nucleotide exchange factor 5*ENSDARG0000007527110
rapgefl1 / Rap guanine nucleotide exchange factor (GEF)-like 1 / Q68EF8* / Q9UHV5* / Rap guanine nucleotide exchange factor like 1*ENSDARG0000007991210
Q6DHR3 / rasgef1ba / RasGEF domain family, member 1Ba / Q8JZL7* / Q0VAM2* / RASGEF1B* / RasGEF domain family member 1B* / Ras-GEF domain-containing family member 1B *ENSDARG000000336148
Q6DBW1 / rasgef1bb / RasGEF domain family, member 1Bb / Q8JZL7* / Q0VAM2* / RASGEF1B* / RasGEF domain family member 1B* / Ras-GEF domain-containing family member 1B *ENSDARG000000442518
rasgrp4 / RAS guanyl releasing protein 4 / Q8BTM9* / Q8TDF6*ENSDARG000000617967
rasgrp3 / RAS guanyl releasing protein 3 (calcium and DAG-regulated) / Q8IV61* / RAS guanyl releasing protein 3*ENSDARG000000778647
rasgrp2 / RAS guanyl releasing protein 2 (calcium and DAG-regulated) / Q7LDG7* / Q9QUG9* / RAS guanyl releasing protein 2*ENSDARG000000623285
RASGRP2 / RAS guanyl releasing protein 2 / Q7LDG7*ENSDARG000000990925


Protein motifs (from Interpro)
Interpro ID Name
 IPR000159  Ras-associating (RA) domain
 IPR000595  Cyclic nucleotide-binding domain
 IPR000651  Ras-like guanine nucleotide exchange factor, N-terminal
 IPR001478  PDZ domain
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR014710  RmlC-like jelly roll fold
 IPR018490  Cyclic nucleotide-binding-like
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily


Gene Ontology (GO)
cell communicationcellular response to stimulusregulation of molecular functioncell communicationcellular response to stimulusregulation of molecular functioncell communicationcellular response to stimulusregulation of molecular functioncell communicationcellular response to stimulusregulation of molecular functioncell communicationcellular response to stimulusregulation of molecular functioncell communicationcellular response to stimulusregulation of molecular functioncell communicationcellular response to stimulusregulation of molecular functioncell communicationcellular response to stimulusregulation of molecular functioncell communicationcellular response to stimulusregulation of molecular functioncell communicationcellular response to stimulusregulation of molecular functioncell communicationcell communicationcellular response to stimuluscellular response to stimulusregulation of molecular functionregulation of molecular function
protein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingprotein bindingenzyme regulator activityenzyme regulator activity
cellcellcellcellcellcellcellcellcellcellcellcell
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0017034 Rap guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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