ENSDARG00000061758


Danio rerio

Features
Gene ID: ENSDARG00000061758
  
Biological name :sh3pxd2ab
  
Synonyms : SH3 and PX domains 2Ab / sh3pxd2ab
  
Possible biological names infered from orthology : O89032 / Q5TCZ1 / SH3 and PX domain-containing protein 2A / SH3 and PX domains 2A / SH3PXD2A
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 20522081
Gene end: 20558961
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000128024
NCBI entrez gene - 567923     See in Manteia.
swissprot - X1WCS7
ZFIN ID - ZDB-GENE-101220-1
Ensembl - ENSDARG00000061758
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SH3PXD2AENSGALG00000008293Gallus gallus
 Q5TCZ1ENSG00000107957Homo sapiens
 O89032ENSMUSG00000053617Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sh3pxd2aa / SH3 and PX domains 2Aa / Q5TCZ1* / O89032* / SH3PXD2A* / SH3 and PX domains 2A* / SH3 and PX domain-containing protein 2A *ENSDARG0000006014846
sh3pxd2b / SH3 and PX domains 2B / A1X283* / A2AAY5* / SH3 and PX domain-containing protein 2B *ENSDARG0000010325125
ncf1 / neutrophil cytosolic factor 1 / P14598* / Q09014* / Neutrophil cytosol factor 1 *ENSDARG000000337359
noxo1a / NADPH oxidase organizer 1a / NOXO1* / Q8NFA2* / NADPH oxidase organizer 1*ENSDARG000000412948
noxo1b / NADPH oxidase organizer 1b / NOXO1* / Q8NFA2* / Q8VCM2* / NADPH oxidase organizer 1*ENSDARG000000563748


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR034917  SH3 and PX domain-containing protein 2A
 IPR035450  SH3PXD2A, SH3 domain 1
 IPR035452  SH3PXD2A, SH3 domain 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006801 superoxide metabolic process IBA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0055114 oxidation-reduction process IBA
 biological_processGO:0071800 podosome assembly IBA
 cellular_componentGO:0002102 podosome IBA
 molecular_functionGO:0016176 superoxide-generating NADPH oxidase activator activity IBA
 molecular_functionGO:0035091 phosphatidylinositol binding IBA


Pathways (from Reactome)
Pathway description
Invadopodia formation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000067545 adam19b / ADAM metallopeptidase domain 19b / ADAM19* / O35674* / Q9H013* / ADAM metallopeptidase domain 19* / Disintegrin and metalloproteinase domain-containing protein 19 *  / complex / reaction
 ENSDARG00000089213 adam15 / ADAM metallopeptidase domain 15 / O88839* / Q13444* / Disintegrin and metalloproteinase domain-containing protein 15 *  / complex / reaction






 

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