ENSDARG00000061848


Danio rerio

Features
Gene ID: ENSDARG00000061848
  
Biological name :col15a1b
  
Synonyms : col15a1b / collagen, type XV, alpha 1b
  
Possible biological names infered from orthology : COL15A1 / Collagen alpha-1(XV) chain Restin / collagen type XV alpha 1 chain / O35206 / P39059
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 23936954
Gene end: 24022085
  
Corresponding Affymetrix probe sets: Dr.4832.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000083076
Ensembl peptide - ENSDARP00000122740
Ensembl peptide - ENSDARP00000153703
swissprot - F1QM25
swissprot - F1QT12
ZFIN ID - ZDB-GENE-070912-689
Ensembl - ENSDARG00000061848
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 COL15A1ENSGALG00000034119Gallus gallus
 P39059ENSG00000204291Homo sapiens
 O35206ENSMUSG00000028339Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
col18a1a / collagen type XVIII alpha 1 chain a / P39061* / P39060* / COL18A1* / collagen type XVIII alpha 1 chain* / Collagen alpha-1(XVIII) chain Endostatin Non-collagenous domain 1*ENSDARG0000003655842
col18a1b / collagen type XVIII alpha 1 chain b / P39060* / COL18A1* / collagen type XVIII alpha 1 chain*ENSDARG0000009590128


Protein motifs (from Interpro)
Interpro ID Name
 IPR001791  Laminin G domain
 IPR008160  Collagen triple helix repeat
 IPR010515  Collagenase NC10/endostatin
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001654 eye development IMP
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:1905812 regulation of motor neuron axon guidance IMP
 cellular_componentGO:0005581 collagen trimer IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0005198 structural molecule activity IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Collagen biosynthesis and modifying enzymes
Assembly of collagen fibrils and other multimeric structures
Collagen chain trimerization


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000217 inner ear inner ear morphology , abnormal
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 ZFA:0000610 vertical myoseptum vertical myoseptum absent , abnormal
vertical myoseptum decreased amount , abnormal
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 ZFA:0001056 myotome myotome has extra parts of type muscle pioneer , abnormal
myotome skeletal muscle cell differentiation process quality , abnormal
myotome extracellular matrix absent , abnormal
myotome atrophied , abnormal
myotome skeletal muscle tissue development decreased process quality , abnormal
myotome slow muscle cell shape , abnormal
myotome fast muscle cell decreased area , abnormal
myotome medial side absent , abnormal
myotome medial side decreased amount , abnormal
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 ZFA:0001086 muscle pioneer muscle pioneer increased distribution , abnormal
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 ZFA:0001094 whole organism whole organism decreased amount , abnormal
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 ZFA:0009117 fast muscle cell fast muscle cell has fewer parts of type fast muscle cell skeletal muscle myofibril, abnormal
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 ZFA:0009243 CaP motoneuron CaP motoneuron axon truncated , abnormal
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 ZFA:0009244 primary motor neuron primary motor neuron motor neuron axon guidance decreased process quality , abnormal
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 ZFA:0009247 secondary motor neuron secondary motor neuron motor neuron axon guidance decreased process quality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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