ENSDARG00000061862


Danio rerio

Features
Gene ID: ENSDARG00000061862
  
Biological name :myo18ab
  
Synonyms : myo18ab / myosin XVIIIAb
  
Possible biological names infered from orthology : MYO18A / myosin XVIIIA / Q92614 / Q9JMH9
  
Species: Danio rerio
  
Chr. number: 15
Strand: 1
Band:
Gene start: 23947932
Gene end: 24120921
  
Corresponding Affymetrix probe sets: Dr.2419.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000083081
Ensembl peptide - ENSDARP00000128019
Ensembl peptide - ENSDARP00000144961
swissprot - E7FE29
swissprot - X1WCS2
ZFIN ID - ZDB-GENE-080423-1
Ensembl - ENSDARG00000061862
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MYO18AENSGALG00000003741Gallus gallus
 MYO18AENSG00000196535Homo sapiens
 Myo18aENSMUSG00000000631Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
myo18aa / myosin XVIIIAa / Q9JMH9* / MYO18A* / Q92614* / myosin XVIIIA*ENSDARG0000007575263
myhc4 / myosin heavy chain 4ENSDARG0000003543816
myhz1.1 / myosin, heavy polypeptide 1.1, skeletal muscleENSDARG0000006799016
myhz1.2 / myosin, heavy polypeptide 1.2, skeletal muscleENSDARG0000006799516
myha / myosin, heavy chain aENSDARG0000009593016
zgc:66156ENSDARG000000952176
CABZ01102039.1ENSDARG000000763572
CABZ01079178.1ENSDARG000001113862
CU633479.6ENSDARG000001148181


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR001478  PDZ domain
 IPR001609  Myosin head, motor domain
 IPR002928  Myosin tail
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031244  Unconventional myosin-XVIIIa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0007030 Golgi organization IGI
 biological_processGO:0007160 cell-matrix adhesion IGI
 biological_processGO:0014866 skeletal myofibril assembly IMP
 biological_processGO:0048741 skeletal muscle fiber development IMP
 biological_processGO:0060415 muscle tissue morphogenesis IMP
 cellular_componentGO:0016459 myosin complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000135 notochord notochord morphology , abnormal
Show

 ZFA:0000155 somite somite patchy , abnormal
Show

 ZFA:0000610 vertical myoseptum vertical myoseptum morphology , abnormal
vertical myoseptum morphology , exacerbated
Show

 ZFA:0001094 whole organism whole organism anterior-posterior axis shortened , abnormal
whole organism anterior-posterior axis bent , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001115 trunk trunk bent , abnormal
Show

 ZFA:0001462 somite border somite border spatial pattern , abnormal
somite border irregular spatial pattern , abnormal
Show

 ZFA:0009114 muscle cell muscle cell disorganized , abnormal
muscle cell detached from myotome , abnormal
muscle cell misaligned with somite , abnormal
muscle cell detached from somite border , abnormal
muscle cell disorganized , exacerbated
Show

 ZFA:0009116 slow muscle cell slow muscle cell spatial pattern , abnormal
slow muscle cell disorganized , abnormal
slow muscle cell disorganized , exacerbated
Show

 ZFA:0009117 fast muscle cell fast muscle cell spatial pattern , abnormal
fast muscle cell disorganized , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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