ENSDARG00000061941


Danio rerio

Features
Gene ID: ENSDARG00000061941
  
Biological name :trpv4
  
Synonyms : transient receptor potential cation channel, subfamily V, member 4 / trpv4
  
Possible biological names infered from orthology : Q9EPK8 / Q9HBA0
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 19795977
Gene end: 19833310
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000121795
NCBI entrez gene - 557850     See in Manteia.
RefSeq - NM_001042730
RefSeq Peptide - NP_001036195
swissprot - A2BG42
ZFIN ID - ZDB-GENE-030912-7
Ensembl - ENSDARG00000061941
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TRPV4ENSGALG00000036360Gallus gallus
 TRPV4ENSG00000111199Homo sapiens
 Trpv4ENSMUSG00000014158Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
trpv1 / transient receptor potential cation channel, subfamily V, member 1 / TRPV2* / Q9Y5S1* / Q9WTR1* / Q8NER1* / Q704Y3* / transient receptor potential cation channel subfamily V member 2*ENSDARG0000005988339
trpv6 / transient receptor potential cation channel, subfamily V, member 6 / TRPV5* / P69744* / Q9H1D0* / Q9NQA5* / Q91WD2* / transient receptor potential cation channel subfamily V member 5*ENSDARG0000001449622


Protein motifs (from Interpro)
Interpro ID Name
 IPR002110  Ankyrin repeat
 IPR004729  Transient receptor potential channel
 IPR005821  Ion transport domain
 IPR008347  Transient receptor potential channel, vanilloid 1-4
 IPR008348  Transient receptor potential channel, vanilloid 4
 IPR020683  Ankyrin repeat-containing domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003171 atrioventricular valve development IMP
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006874 cellular calcium ion homeostasis IBA
 biological_processGO:0006970 response to osmotic stress IMP
 biological_processGO:0007015 actin filament organization IBA
 biological_processGO:0007231 osmosensory signaling pathway IBA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:0071476 cellular hypotonic response IBA
 biological_processGO:0097704 cellular response to oscillatory fluid shear stress IMP
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0005929 cilium IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005262 calcium channel activity IBA


Pathways (from Reactome)
Pathway description
TRP channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain hydrocephalic , abnormal
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 ZFA:0000037 anatomical structure anatomical structure decreased amount , abnormal
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 ZFA:0001094 whole organism whole organism decreased life span , abnormal
Show

 ZFA:0001315 atrioventricular canal atrioventricular canal decreased amount , abnormal
Show

 ZFA:0001616 atrioventricular canal endocardium atrioventricular canal endocardium endothelial cell decreased amount , abnormal
atrioventricular canal endocardium decreased amount , abnormal
Show

 ZFA:0005064 atrioventricular valve atrioventricular valve morphology , abnormal
atrioventricular valve shape , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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