ENSDARG00000061992


Danio rerio

Features
Gene ID: ENSDARG00000061992
  
Biological name :dot1l
  
Synonyms : dot1l / DOT1-like histone H3K79 methyltransferase
  
Possible biological names infered from orthology : DOT1 like histone lysine methyltransferase / Q8TEK3
  
Species: Danio rerio
  
Chr. number: 22
Strand: -1
Band:
Gene start: 20782915
Gene end: 20838011
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000150531
Ensembl peptide - ENSDARP00000083509
Ensembl peptide - ENSDARP00000117281
Ensembl peptide - ENSDARP00000154602
swissprot - F1Q4W7
swissprot - A8E7B7
ZFIN ID - ZDB-GENE-060503-341
Ensembl - ENSDARG00000061992
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DOT1LENSGALG00000000843Gallus gallus
 DOT1LENSG00000104885Homo sapiens
 Dot1lENSMUSG00000061589Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR025789  Histone-lysine N-methyltransferase DOT1 domain
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase
 IPR030445  Histone H3-K79 methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000077 DNA damage checkpoint IBA
 biological_processGO:0006281 DNA repair IBA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006348 chromatin silencing at telomere IBA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0034729 histone H3-K79 methylation IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IMP
 biological_processGO:0060729 intestinal epithelial structure maintenance IMP
 biological_processGO:2000677 regulation of transcription regulatory region DNA binding IBA
 cellular_componentGO:0000781 chromosome, telomeric region IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0018024 histone-lysine N-methyltransferase activity IEA
 molecular_functionGO:0031151 histone methyltransferase activity (H3-K79 specific) IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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